Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.85 |
| ▸ | CYP1A1 | P04798 | 5/20 | 0.85 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.85 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.85 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.85 |
| ▸ | LMNA | P02545 | 3/20 | 0.85 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.85 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.79 |
| ▸ | TTR | P02766 | 4/20 | 0.79 |
| ▸ | NQO2 | P16083 | 4/20 | 0.76 |
| ▸ | MEN1 | O00255 | 4/20 | 0.76 |
| ▸ | MAPT | P10636 | 4/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.76 |
| ▸ | ABL1 | P00519 | 3/20 | 0.76 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.76 |
| ▸ | BCR | P11274 | 3/20 | 0.76 |
| ▸ | NPC1 | O15118 | 2/20 | 0.76 |
| ▸ | GAA | P10253 | 2/20 | 0.76 |
| ▸ | RAB9A | P51151 | 2/20 | 0.76 |
| ▸ | GFER | P55789 | 2/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Resveratrol 4'-Methyl Ether SCHEMBL563261 | 0.92 | PTGS2 (1.00) | PTGS2CYP1A1CYP1B1KDM4EPTGS1 | |
| Resveratrol 4'-Methyl Ether SCHEMBL563262 | 0.92 | PTGS2 (1.00) | PTGS2CYP1A1CYP1B1KDM4EPTGS1 | |
| Resveratrol 4'-Methyl Ether SCHEMBL4732963 | 0.92 | PTGS2 (1.00) | PTGS2CYP1A1CYP1B1KDM4EPTGS1 | |
| SCHEMBL8396878 | 0.92 | PTGS2 (0.77) | PTGS2CYP1A1CYP1B1KDM4EPTGS1 | |
| SCHEMBL12567384 | 0.92 | PTGS2 (0.77) | PTGS2CYP1A1CYP1B1KDM4EPTGS1 | |
| SCHEMBL8396882 | 0.92 | PTGS2 (0.77) | PTGS2CYP1A1CYP1B1KDM4EPTGS1 | |
| SCHEMBL2516449 | 0.89 | PTGS2 (0.86) | PTGS2CYP1A1CYP1B1KDM4EPTGS1 | |
| SCHEMBL562336 | 0.89 | CYP1A1 (1.00) | PTGS2CYP1A1CYP1B1KDM4EPTGS1 | |
| SCHEMBL2516446 | 0.89 | PTGS2 (0.86) | PTGS2CYP1A1CYP1B1KDM4EPTGS1 | |
| SCHEMBL562335 | 0.89 | CYP1A1 (1.00) | PTGS2CYP1A1CYP1B1KDM4EPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130150628-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A CURCUMIN DERIVATIVE | DIMAURO THOMAS M (US) | 2013-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130150628-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A CURCUMIN DERIVATIVE | CPT1A, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, ABCB1 | PTGS2 112/4885CYP1A1 219/4885CYP1B1 163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.