Resveratrol 4'-Methyl Ether

Resveratrol 4'-Methyl Ether

SCHEMBL563262

COc1ccc(C=Cc2cc(O)cc(O)c2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 6/20 1.00
CYP1A1 P04798 5/20 1.00
CYP1B1 Q16678 5/20 1.00
KDM4E B2RXH2 5/20 1.00
PTGS1 P23219 4/20 1.00
LMNA P02545 3/20 1.00
ALOX12 P18054 1/20 1.00
ALOX5 P09917 5/20 0.72
TTR P02766 4/20 0.72
NQO2 P16083 4/20 0.70
ESR1 P03372 3/20 0.70
ABL1 P00519 3/20 0.70
ABCB1 P08183 3/20 0.70
BCR P11274 3/20 0.70
CYP1A2 P05177 3/20 0.70
CYP19A1 P11511 2/20 0.70
AHR P35869 2/20 0.70
TUBB1 Q9H4B7 2/20 0.70
TUBB4A P04350 1/20 0.70
TUBB P07437 1/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Resveratrol 4'-Methyl Ether SCHEMBL4732963 1.00 PTGS2 (1.00) PTGS2CYP1A1CYP1B1KDM4EPTGS1
Resveratrol 4'-Methyl Ether SCHEMBL563261 1.00 PTGS2 (1.00) PTGS2CYP1A1CYP1B1KDM4EPTGS1
SCHEMBL15026080 0.92 PTGS2 (0.85) PTGS2CYP1A1CYP1B1KDM4EPTGS1
SCHEMBL29652111 0.92 PTGS2 (0.86) PTGS2CYP1A1CYP1B1KDM4EPTGS1
SCHEMBL2516446 0.92 PTGS2 (0.86) PTGS2CYP1A1CYP1B1KDM4EPTGS1
SCHEMBL2516449 0.92 PTGS2 (0.86) PTGS2CYP1A1CYP1B1KDM4EPTGS1
SCHEMBL29662231 0.92 PTGS2 (0.86) PTGS2CYP1A1CYP1B1KDM4EPTGS1
SCHEMBL12307322 0.89 PTGS2 (0.79) PTGS2CYP1A1CYP1B1KDM4EPTGS1
SCHEMBL8396878 0.87 PTGS2 (0.77) PTGS2CYP1A1CYP1B1KDM4EPTGS1
SCHEMBL12567384 0.87 PTGS2 (0.77) PTGS2CYP1A1CYP1B1KDM4EPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2679243-B1 Co-precipitate of one or more stilbene polyphenols in lamellar anionic solids, it's applications and related preparation method FIORETTI BERNARD (IT) 2017-05-24 EP claimed
US-20120178704-A1 PREVENTION AND TREATMENT OF COLON CANCER RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY 2012-07-12 US claimed
US-20110256115-A1 HYDROSOLUBLE [6)O-ALPHA-D-GLCP-(1->]N-6-O-BETA-D-GLCP-(1->-PHENOLIC DERIVATIVES WITH DERMOCOSMETIC, NUTRITIONAL AND THERAPEUTIC APPLICATIONS, AND COMPOSITIONS CONTAINING SAID WATER SOLUBLE COMPOUNDS LIBRAGEN (FR) 2011-10-20 US claimed
EP-2202237-A1 Hydrosoluble [6)-O-alpha-d-glcp-(1->]n-6-o-bêta-d-glcp-(1->-phenllic derivatives with dermocosmetic, nutritional and therapeutic applications, and compositions containing said water soluble compounds Libragen (FR) 2010-06-30 EP claimed
US-20080139650-A1 Fungicidally Active Polymer Dispersions And Use Thereof CELANESE EMULSIONS GMBH (DE) 2008-06-12 US claimed
WO-2008070872-A1 PREVENTION AND TREATMENT OF COLON CANCER RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2008-06-12 WO claimed
EP-4743071-A2 DIPHENYLETHYLENE COMPOUNDS AND COMPOSITIONS THEREOF INNOVENE INC. (US) 2026-05-20 EP disclosed
WO-2025015023-A2 DIPHENYLETHYLENE COMPOUNDS AND COMPOSITIONS THEREOF INNOVENE, INC. (US) 2025-01-16 WO disclosed
EP-3280402-B1 TOLAN COMPOUNDS FOR PROMOTING WOUND HEALING BIOMENDICS LLC (US) 2024-06-05 EP disclosed
CN-116515752-B Use of 3, 5-dihydroxy-4' -methoxystilbene-3-O-beta-D-glucoside for promoting proliferation of DC cells in vitro 沃森克里克(北京)生物科技有限公司 2023-10-24 CN disclosed
WO-2023150072-A1 COMPOSITIONS AND METHODS FOR THE PRESERVATION OF PLANT MATTER SINCLAIR DAVID A (US) 2023-08-10 WO disclosed
CN-116515752-A Use of 3, 5-dihydroxy-4' -methoxystilbene-3-O-beta-D-glucoside for promoting proliferation of DC cells in vitro 沃森克里克(北京)生物科技有限公司 2023-08-01 CN disclosed
US-11129781-B2 Agent for hair deforming treatment KAO CORPORATION (JP) 2021-09-28 US disclosed
US-20050240062-A1 Structural modification of resveratrol: Sodium resverastatin phosphate NATIONAL INSTITUTES OF HEALTH 2005-10-27 US disclosed
US-20050136537-A1 Compositions for manipulating the lifespan and stress response of cells and organisms PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2005-06-23 US disclosed
US-20050096256-A1 Compositions for manipulating the lifespan and stress response of cells and organisms PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2005-05-05 US disclosed
WO-2005002672-A2 SIRT1 MODULATORS FOR MANIPULATING CELLS/ORGANISM LIFESPAN/STRESS RESPONSE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2005-01-13 WO disclosed
WO-2005002555-A2 SIRT1 MODULATORS FOR MANIPULATING CELL/ORGANISM LIFESPAN/STRESS RESPONSE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2005-01-13 WO disclosed
WO-2003086414-A1 STRUCTURAL MODIFICATION OF RESVERATROL: SODIUM RESVERASTATIN PHOSPHATE ARIZONA BOARD OF REGENTS (US) 2003-10-23 WO disclosed
WO-2003086414-A1 STRUCTURAL MODIFICATION OF RESVERATROL: SODIUM RESVERASTATIN PHOSPHATE ARIZONA BOARD OF REGENTS (US) 2003-10-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110256115-A1 HYDROSOLUBLE [6)O-ALPHA-D-GLCP-(1->]N-6-O-BETA-D-GLCP-(1->-PHENOLIC DERIVATIVES WITH DERMOCOSMETIC, NUTRITIONAL AND THERAPEUTIC APPLICATIONS, AND COMPOSITIONS CONTAINING SAID WATER SOLUBLE COMPOUNDS UGGT1, UGDH, CYP24A1 PTGS2 1730/4885CYP1A1 333/4885CYP1B1 578/4885
US-20050240062-A1 Structural modification of resveratrol: Sodium resverastatin phosphate PI4KB, HDAC4, PIK3CA PTGS2 3996/4885CYP1A1 3525/4885CYP1B1 2430/4885
US-20120178704-A1 PREVENTION AND TREATMENT OF COLON CANCER APC, SI, NFKBIA PTGS2 28/4885CYP1A1 1123/4885CYP1B1 1133/4885
US-20080139650-A1 Fungicidally Active Polymer Dispersions And Use Thereof CBR3, CBR1, CYP3A4 PTGS2 3728/4885CYP1A1 5/4885CYP1B1 4/4885
US-20050096256-A1 Compositions for manipulating the lifespan and stress response of cells and organisms SIRT1, SIRT2, FOXO3 PTGS2 2650/4885CYP1A1 4175/4885CYP1B1 4123/4885
US-11129781-B2 Agent for hair deforming treatment GRHPR, SLC26A4, COL1A1 PTGS2 3041/4885CYP1A1 2575/4885CYP1B1 751/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.