Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 5/20 | 0.91 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.91 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.91 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.91 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.91 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.91 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.91 |
| ▸ | LMNA | P02545 | 4/20 | 0.91 |
| ▸ | MAPT | P10636 | 4/20 | 0.91 |
| ▸ | HPGD | P15428 | 4/20 | 0.91 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.91 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.91 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.91 |
| ▸ | TTR | P02766 | 3/20 | 0.91 |
| ▸ | TP53 | P04637 | 3/20 | 0.91 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.91 |
| ▸ | MEN1 | O00255 | 3/20 | 0.91 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.91 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.91 |
| ▸ | THPO | P40225 | 3/20 | 0.91 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1932873 | 1.00 | LCK (0.91) | LCKCYP3A4CYP2C9HIF1AHSD17B10 | |
| Piceatannol SCHEMBL29929133 | 0.95 | LCK (1.00) | LCKCYP3A4CYP2C9HIF1AHSD17B10 | |
| Piceatannol SCHEMBL43541 | 0.95 | LCK (1.00) | LCKCYP3A4CYP2C9HIF1AHSD17B10 | |
| Piceatannol SCHEMBL29754702 | 0.95 | LCK (1.00) | LCKCYP3A4CYP2C9HIF1AHSD17B10 | |
| Piceatannol SCHEMBL505561 | 0.95 | LCK (1.00) | LCKCYP3A4CYP2C9HIF1AHSD17B10 | |
| Piceatannol SCHEMBL29501290 | 0.95 | LCK (1.00) | LCKCYP3A4CYP2C9HIF1AHSD17B10 | |
| Piceatannol SCHEMBL19953785 | 0.95 | LCK (1.00) | LCKCYP3A4CYP2C9HIF1AHSD17B10 | |
| SCHEMBL13409618 | 0.89 | LCK (0.72) | LCKCYP3A4CYP2C9HIF1AHSD17B10 | |
| SCHEMBL31706727 | 0.88 | LCK (1.00) | LCKCYP3A4CYP2C9HIF1AHSD17B10 | |
| SCHEMBL30631591 | 0.88 | LCK (1.00) | LCKCYP3A4CYP2C9HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190218181-A1 | PROCESS FOR THE MANUFACTURE OF HYDROXY-SUBSTITUTED AROMATIC COMPOUNDS | BASF PERSONAL CARE AND NUTRITION GMBH (DE) | 2019-07-18 | — | — | US | disclosed |
| US-20190218181-A1 | PROCESS FOR THE MANUFACTURE OF HYDROXY-SUBSTITUTED AROMATIC COMPOUNDS | BASF PERSONAL CARE AND NUTRITION GMBH (DE) | 2019-07-18 | — | — | US | disclosed |
| EP-3455201-A1 | PROCESS FOR THE MANUFACTURE OF HYDROXY-SUBSTITUTED AROMATIC COMPOUNDS | BASF SE (DE) | 2019-03-20 | — | — | EP | disclosed |
| WO-2017194590-A1 | PROCESS FOR THE MANUFACTURE OF HYDROXY-SUBSTITUTED AROMATIC COMPOUNDS | BASF SE (DE) | 2017-11-16 | — | — | WO | disclosed |
| WO-2017194590-A1 | PROCESS FOR THE MANUFACTURE OF HYDROXY-SUBSTITUTED AROMATIC COMPOUNDS | BASF SE (DE) | 2017-11-16 | — | — | WO | disclosed |
| US-20170224637-A1 | INTRANSAL DELIVERY OF CURCUMIN | DePuy Synthes Products, Inc. (US) | 2017-08-10 | — | — | US | disclosed |
| US-20140163116-A1 | METHOD OF TREATING CANCER USING A CURCUMIN DERIVATIVE | DePuy Synthes Products, LLC (US) | 2014-06-12 | — | — | US | disclosed |
| US-20140057994-A1 | COMPOSITIONS COMPRISING SUBSTITUTED PHENOLS AND TOPICAL APPLICATION THEREOF | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2014-02-27 | — | — | US | disclosed |
| US-20140057994-A1 | COMPOSITIONS COMPRISING SUBSTITUTED PHENOLS AND TOPICAL APPLICATION THEREOF | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2014-02-27 | — | — | US | disclosed |
| US-20130150628-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A CURCUMIN DERIVATIVE | DIMAURO THOMAS M (US) | 2013-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140057994-A1 | COMPOSITIONS COMPRISING SUBSTITUTED PHENOLS AND TOPICAL APPLICATION THEREOF | TYR, S100A4, S100A6 | LCK 2037/4885CYP3A4 783/4885CYP2C9 635/4885 |
| US-20130150628-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A CURCUMIN DERIVATIVE | CPT1A, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, ABCB1 | LCK 4307/4885CYP3A4 40/4885CYP2C9 18/4885 |
| US-20140163116-A1 | METHOD OF TREATING CANCER USING A CURCUMIN DERIVATIVE | HDAC5, HDAC6, CPT1A | LCK 3096/4885CYP3A4 920/4885CYP2C9 546/4885 |
| US-20190218181-A1 | PROCESS FOR THE MANUFACTURE OF HYDROXY-SUBSTITUTED AROMATIC COMPOUNDS | HPD, HAAO, PAH | LCK 1632/4885CYP3A4 14/4885CYP2C9 50/4885 |
| US-20170224637-A1 | INTRANSAL DELIVERY OF CURCUMIN | FABP7, FABP2, NDUFB5 | LCK 4207/4885CYP3A4 3413/4885CYP2C9 3193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.