Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.38 |
| ▸ | TLR4 | O00206 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16871076 | 0.83 | AOC3 (0.48) | HIF1ACYP2D6SLC22A1OPRM1 | |
| SCHEMBL16871039 | 0.83 | AOC3 (0.48) | HIF1ACYP2D6SLC22A1OPRM1 | |
| SCHEMBL16871041 | 0.83 | AOC3 (0.48) | HIF1ACYP2D6SLC22A1OPRM1 | |
| SCHEMBL15026291 | 0.83 | AOC3 (0.48) | HIF1ACYP2D6SLC22A1OPRM1 | |
| SCHEMBL15008984 | 0.82 | ALOX5 (0.47) | SMN1; SMN2PTGESALOX5 | |
| SCHEMBL15024186 | 0.82 | ALOX5 (0.47) | SMN1; SMN2PTGESALOX5 | |
| SCHEMBL16871387 | 0.82 | ALOX5 (0.47) | SMN1; SMN2PTGESALOX5 | |
| SCHEMBL15026292 | 0.81 | CACNA1B (0.46) | KDM4EALDH1A1LMNASMN1; SMN2CACNA1B | |
| SCHEMBL15474067 | 0.81 | SLC22A1 (0.59) | KDM4EALDH1A1LMNASMN1; SMN2CACNA1B | |
| Hydrochloric Acid SCHEMBL15008699 | 0.81 | ALOX5 (0.46) | SMN1; SMN2HIF1APTGESALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013090161-A1 | STEREOSELECTIVE SYNTHESIS OF TAPENTADOL AND ITS SALTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-06-20 | — | — | WO | disclosed |
| US-20130150622-A1 | STEREOSELECTIVE SYNTHESIS OF TAPENTADOL AND ITS SALTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130150622-A1 | STEREOSELECTIVE SYNTHESIS OF TAPENTADOL AND ITS SALTS | SLC6A2, SLC6A4, SLC6A6 | KDM4E 1955/4885ALDH1A1 891/4885LMNA 4683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.