Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | TLR4 | O00206 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ACACA | Q13085 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28238509 | 0.82 | CACNA1B (0.50) | CACNA1BALOX5PTGESPPARGPPARA | |
| SCHEMBL15026266 | 0.81 | KDM4E (0.44) | CACNA1BALOX5PTGESPPARGPPARA | |
| SCHEMBL15009016 | 0.81 | BCHE (0.52) | ALOX5KDM4EALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL15024190 | 0.81 | BCHE (0.52) | ALOX5KDM4EALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL27954038 | 0.80 | CHRM2 (0.45) | SMN1; SMN2 | |
| SCHEMBL16961945 | 0.80 | TSHR (0.46) | CACNA1BALOX5PTGESPPARGPPARA | |
| SCHEMBL28035867 | 0.78 | CYSLTR2 (0.52) | CACNA1BALOX5PTGESPPARGPPARA | |
| SCHEMBL16950919 | 0.77 | TSHR (0.51) | CACNA1BALOX5PTGESPPARGPPARA | |
| SCHEMBL12652785 | 0.77 | KDM4E (0.67) | CACNA1BALOX5PTGESPPARGPPARA | |
| SCHEMBL25080975 | 0.75 | CACNA1B (0.54) | CACNA1BALOX5PTGESPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013090161-A1 | STEREOSELECTIVE SYNTHESIS OF TAPENTADOL AND ITS SALTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-06-20 | — | — | WO | disclosed |
| US-20130150622-A1 | STEREOSELECTIVE SYNTHESIS OF TAPENTADOL AND ITS SALTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130150622-A1 | STEREOSELECTIVE SYNTHESIS OF TAPENTADOL AND ITS SALTS | SLC6A2, SLC6A4, SLC6A6 | CACNA1B 182/4885ALOX5 1488/4885PTGES 230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.