Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | BLM | P54132 | 2/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.61 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | DRD1 | P21728 | 1/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.61 |
| ▸ | DRD3 | P35462 | 1/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.61 |
| ▸ | EYA2 | O00167 | 1/20 | 0.56 |
| ▸ | APP | P05067 | 1/20 | 0.56 |
| ▸ | ACE | P12821 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21775921 | 0.93 | TDP1 (0.56) | TDP1BLMPMP22TSHRKDM4E | |
| SCHEMBL8700272 | 0.93 | TDP1 (0.70) | TDP1BLMPMP22TSHRKDM4E | |
| SCHEMBL24896776 | 0.93 | TDP1 (0.70) | TDP1BLMPMP22TSHRKDM4E | |
| SCHEMBL15026437 | 0.93 | TDP1 (0.70) | TDP1BLMPMP22TSHRKDM4E | |
| SCHEMBL114039 | 0.91 | TDP1 (0.75) | TDP1BLMPMP22TSHRKDM4E | |
| SCHEMBL22313963 | 0.90 | TDP1 (0.50) | TDP1BLMPMP22TSHRKDM4E | |
| SCHEMBL16390628 | 0.88 | TDP1 (0.59) | TDP1BLMPMP22TSHRKDM4E | |
| SCHEMBL11515399 | 0.88 | TDP1 (0.74) | TDP1BLMPMP22TSHRKDM4E | |
| SCHEMBL29520752 | 0.86 | DNM1 (0.50) | TDP1BLMPMP22TSHRKDM4E | |
| SCHEMBL5557442 | 0.85 | TDP1 (0.83) | TDP1BLMPMP22TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013082655-A1 | FUNCTIONALISATION OF CAGE AMINE LIGANDS FOR METALLO-RADIOPHARMACEUTICALS | THE UNIVERSITY OF MELBOURNE (AU) | 2013-06-13 | — | — | WO | disclosed |
| WO-2013082656-A1 | CAGE AMINE LIGANDS FOR METALLO-RADIOPHARMACEUTICALS | THE UNIVERSITY OF MELBOURNE (AU) | 2013-06-13 | — | — | WO | disclosed |