SCHEMBL11515399

SCHEMBL11515399

CN(C)CCN(CC(=O)O)CC(=O)O

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.74
EYA2 O00167 1/20 0.74
APP P05067 1/20 0.74
ACE P12821 1/20 0.74
BLM P54132 2/20 0.70
PMP22 Q01453 2/20 0.70
CHRM2 P08172 2/20 0.70
KDM4E B2RXH2 1/20 0.70
LMNA P02545 1/20 0.70
ADRA2A P08913 1/20 0.70
ALOX15 P16050 1/20 0.70
TSHR P16473 1/20 0.70
DRD1 P21728 1/20 0.70
SLC6A2 P23975 1/20 0.70
SLC6A4 P31645 1/20 0.70
CYP2C19 P33261 1/20 0.70
ADRA1A P35348 1/20 0.70
DRD3 P35462 1/20 0.70
SLC6A3 Q01959 1/20 0.70
HRH3 Q9Y5N1 1/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL114039 0.97 TDP1 (0.75) TDP1EYA2APPACEBLM
SCHEMBL24896776 0.95 TDP1 (0.70) TDP1EYA2APPACEBLM
SCHEMBL8700272 0.95 TDP1 (0.70) TDP1EYA2APPACEBLM
SCHEMBL15026437 0.95 TDP1 (0.70) TDP1EYA2APPACEBLM
SCHEMBL14392744 0.93 TDP1 (0.64) TDP1EYA2APPACEBLM
SCHEMBL19700801 0.91 TDP1 (0.61) TDP1EYA2APPACEBLM
Edetic Acid SCHEMBL10785292 0.89 TDP1 (0.82) TDP1EYA2APPACEBLM
Edetic Acid SCHEMBL7521838 0.89 TDP1 (0.82) TDP1EYA2APPACEBLM
SCHEMBL11961185 0.89 TDP1 (0.58) TDP1EYA2APPACEBLM
SCHEMBL19700802 0.89 TDP1 (0.62) TDP1EYA2APPACEBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117917989-A Use of a reversible metal electrodeposited electrolyte with pH-adjustable, dynamic glass element with high opacity and excellent rest stability, and electrolyte useful therefor 代表内华达大学雷诺分校的内华达高等教育系统董事会 2024-04-23 CN disclosed
EP-4323615-A1 DYNAMIC GLASS ELEMENT USING REVERSIBLE METAL ELECTRODEPOSITION ELECTROLYTES WITH TUNABLE PH WITH HIGH OPACITY AND EXCELLENT RESTING STABILITY AND ELECTROLYTES USEFUL THEREFORE Board of Regents of the Nevada System of Higher Education, on Behalf of the University of Nevada, Reno (US) 2024-02-21 EP disclosed
US-20230355815-A1 ACTIVE DELIVERY OF RADIOTRACERS ACROSS THE BLOOD BRAIN BARRIER THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2023-11-09 US disclosed
WO-2022221094-A1 DYNAMIC GLASS ELEMENT USING REVERSIBLE METAL ELECTRODEPOSITION ELECTROLYTES WITH TUNABLE PH WITH HIGH OPACITY AND EXCELLENT RESTING STABILITY AND ELECTROLYTES USEFUL THEREFORE THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE UNIVERSITY OF NEVADA, RENO (US) 2022-10-20 WO disclosed
US-20170119913-A1 CONJUGATE COMPRISING A NEUROTENSIN RECEPTOR LIGAND AND USE THEREOF 3B PHARMACEUTICALS GMBH (DE) 2017-05-04 US disclosed
US-9480758-B2 Diagnostic agents selective against metalloproteases BRACCO IMAGING S.P.A. (IT) 2016-11-01 US disclosed
US-9376373-B2 Vinyl monomers having chelating functionality Rohm and Haas Company Dow Global Technologies LLC 2016-06-28 US disclosed
US-9346899-B2 Polymers having chelating functionality ROHM AND HAAS COMPANY 2016-05-24 US disclosed
US-20150376116-A1 VINYL MONOMERS HAVING CHELATING FUNCTIONALITY ROHM AND HAAS COMPANY 2015-12-31 US disclosed
US-20150299133-A1 NEUROTENSIN RECEPTOR LIGANDS 3 B Pharmaceuticals GmbH 2015-10-22 US disclosed
US-20140308304-A1 LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS ALNYLAM PHARMACEUTICALS, INC. 2014-10-16 US disclosed
US-20140303397-A1 VINYL MONOMERS HAVING CHELATING FUNCTIONALITY ROHM AND HAAS COMPANY (US) 2014-10-09 US disclosed
US-20140303337-A1 POLYMERS HAVING CHELATING FUNCTIONALITY ROHM AND HAAS COMPANY (US) 2014-10-09 US disclosed
US-20110117015-A1 Diagnostic Agents Selective Against Metalloproteases BRACCO IMAGING S.P.A. (IT) 2011-05-19 US disclosed
US-4142061-A FOR STABILIZING COBALT CABONYL CATALYST CHEVRON RESEARCH COMPANY (US) 1979-02-27 US disclosed
US-4096191-A Hydroformylation of olefins using azoxy-dentated ligands CHEVRON RESEARCH COMPANY (US) 1978-06-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110117015-A1 Diagnostic Agents Selective Against Metalloproteases MMP3, MMP7, MMP9 TDP1 2569/4885EYA2 4495/4885APP 902/4885
US-20230355815-A1 ACTIVE DELIVERY OF RADIOTRACERS ACROSS THE BLOOD BRAIN BARRIER CD209, ARG1, MYADM TDP1 258/4885EYA2 4683/4885APP 41/4885
US-20150299133-A1 NEUROTENSIN RECEPTOR LIGANDS NTSR1, NTSR2, TACR3 TDP1 3351/4885EYA2 4730/4885APP 787/4885
US-20150376116-A1 VINYL MONOMERS HAVING CHELATING FUNCTIONALITY MVD, MMAB, PAM TDP1 3855/4885EYA2 4677/4885APP 4350/4885
US-20140308304-A1 LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS NPC1L1, NPC1, CETP TDP1 4210/4885EYA2 2252/4885APP 1676/4885
US-20140303397-A1 VINYL MONOMERS HAVING CHELATING FUNCTIONALITY MVD, MMAB, PAM TDP1 3855/4885EYA2 4677/4885APP 4350/4885
US-20170119913-A1 CONJUGATE COMPRISING A NEUROTENSIN RECEPTOR LIGAND AND USE THEREOF NTSR1, NTSR2, ADGRF1 TDP1 2810/4885EYA2 4355/4885APP 592/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.