Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.83 |
| ▸ | BLM | P54132 | 2/20 | 0.83 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.83 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.83 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.83 |
| ▸ | LMNA | P02545 | 1/20 | 0.83 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.83 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.83 |
| ▸ | TSHR | P16473 | 1/20 | 0.83 |
| ▸ | DRD1 | P21728 | 1/20 | 0.83 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.83 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.83 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.83 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.83 |
| ▸ | DRD3 | P35462 | 1/20 | 0.83 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.83 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.83 |
| ▸ | EYA2 | O00167 | 1/20 | 0.78 |
| ▸ | APP | P05067 | 1/20 | 0.78 |
| ▸ | ACE | P12821 | 1/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7869953 | 0.97 | TDP1 (0.78) | TDP1BLMPMP22KDM4EALOX15 | |
| SCHEMBL7872108 | 0.94 | TDP1 (0.74) | TDP1BLMPMP22KDM4EALOX15 | |
| SCHEMBL133510 | 0.94 | TDP1 (0.77) | TDP1BLMPMP22KDM4EALOX15 | |
| Ammonia Solution, Strong SCHEMBL9153466 | 0.92 | TDP1 (0.72) | TDP1BLMPMP22KDM4EALOX15 | |
| Ammonia Solution, Strong SCHEMBL9133460 | 0.92 | TDP1 (0.72) | TDP1BLMPMP22KDM4EALOX15 | |
| Water SCHEMBL8747206 | 0.92 | TDP1 (0.72) | TDP1BLMPMP22KDM4EALOX15 | |
| SCHEMBL9810938 | 0.92 | TDP1 (0.72) | TDP1BLMPMP22KDM4EALOX15 | |
| SCHEMBL5495960 | 0.92 | TDP1 (0.72) | TDP1BLMPMP22KDM4EALOX15 | |
| Potassium SCHEMBL31156528 | 0.92 | TDP1 (0.72) | TDP1BLMPMP22KDM4EALOX15 | |
| SCHEMBL31156529 | 0.92 | TDP1 (0.72) | TDP1BLMPMP22KDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8961928-B2 | Ligand and metal complex having the same | NATIONAL CHIAO TUNG UNIVERSITY (TW) | 2015-02-24 | — | — | US | disclosed |
| US-8877163-B2 | Cycloalkyl triamine pentacarboxylate as ligands for paramagnetic metal complexes | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2014-11-04 | — | — | US | disclosed |
| US-20130303728-A1 | LIGAND AND METAL COMPLEX HAVING THE SAME | NATIONAL CHIAO TUNG UNIVERSITY (TW) | 2013-11-14 | — | — | US | disclosed |
| US-8354512-B2 | Ligand and metal complex | NATIONAL CHIAO TUNG UNIVERSITY (TW) | 2013-01-15 | — | — | US | disclosed |
| US-8354512-B2 | Ligand and metal complex | NATIONAL CHIAO TUNG UNIVERSITY (TW) | 2013-01-15 | — | — | US | disclosed |
| US-20110065905-A1 | Ligand and metal complex | NATIONAL CHIAO TUNG UNIVERSITY (TW) | 2011-03-17 | — | — | US | disclosed |
| US-20110065905-A1 | Ligand and metal complex | NATIONAL CHIAO TUNG UNIVERSITY (TW) | 2011-03-17 | — | — | US | disclosed |
| US-20070207087-A1 | Cycloalkyl triamine pentacarboxylate as ligands for paramagnetic metal complexes | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2007-09-06 | — | — | US | disclosed |
| US-20060034774-A1 | Galactopyrannosyltriaminetetracarboxylate as ligands for bioactivated paramagnetic metal complexes | KAOHSIUNG MEDICAL UNIVERSITY | 2006-02-16 | — | — | US | disclosed |
| US-6303761-B1 | CAN BE USED AS A CONTRAST AGENT FOR MAGNETIC RESONANCE IMAGING; CONTAINING ETHER OR SULFIDE LINKAGES | DEPARTMENT OF HEALTH THE EXECUTIVE YUAN, REPUBLIC OF CHINA (TW) | 2001-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065905-A1 | Ligand and metal complex | CD74, SLC39A14, PYM1 | TDP1 4255/4885BLM 4140/4885PMP22 4036/4885 |
| US-20130303728-A1 | LIGAND AND METAL COMPLEX HAVING THE SAME | MMP12, MMEL1, PLAT | TDP1 2966/4885BLM 3651/4885PMP22 1051/4885 |
| US-20070207087-A1 | Cycloalkyl triamine pentacarboxylate as ligands for paramagnetic metal complexes | SLC39A14, PLPBP, TSPO | TDP1 4657/4885BLM 3311/4885PMP22 32/4885 |
| US-20060034774-A1 | Galactopyrannosyltriaminetetracarboxylate as ligands for bioactivated paramagnetic metal complexes | CSGALNACT1, ST3GAL3, B3GAT3 | TDP1 3766/4885BLM 3201/4885PMP22 1501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.