SCHEMBL15027287

SCHEMBL15027287

CCCCCC(CCCCC)CCOC(=O)CCCCCCCC(CCCCCCCC(=O)OCCC(CCCCC)CCCCC)C(=O)OCCCN1CCCC1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 2/20 0.50
▸ ALDH1A1 P00352 1/20 0.50
▸ DGKA P23743 1/20 0.43
▸ MAPT P10636 1/20 0.40
▸ MAPK1 P28482 1/20 0.40
▸ NPSR1 Q6W5P4 1/20 0.40
▸ THRA P10827 2/20 0.40
▸ THRB P10828 2/20 0.40
▸ HRH2 P25021 6/20 0.39
▸ HRH1 P35367 6/20 0.39
▸ DNM1 Q05193 1/20 0.39
▸ CYP3A4 P08684 1/20 0.39
▸ TSHR P16473 1/20 0.39
▸ ATM Q13315 1/20 0.39
▸ TDP1 Q9NUW8 1/20 0.39
▸ ESR1 P03372 1/20 0.38
▸ PLA2G2A P14555 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24368823 1.00 L3MBTL1 (0.50) L3MBTL1ALDH1A1DGKAMAPTMAPK1
SCHEMBL15027416 1.00 L3MBTL1 (0.50) L3MBTL1ALDH1A1DGKAMAPTMAPK1
SCHEMBL17123991 1.00 L3MBTL1 (0.50) L3MBTL1ALDH1A1DGKAMAPTMAPK1
SCHEMBL15027947 1.00 L3MBTL1 (0.50) L3MBTL1ALDH1A1DGKAMAPTMAPK1
SCHEMBL17123907 1.00 L3MBTL1 (0.50) L3MBTL1ALDH1A1DGKAMAPTMAPK1
SCHEMBL15027372 0.99 ALDH1A1 (0.52) L3MBTL1ALDH1A1DGKAMAPTMAPK1
SCHEMBL15027837 0.99 ALDH1A1 (0.52) L3MBTL1ALDH1A1DGKAMAPTMAPK1
SCHEMBL15027204 0.99 ALDH1A1 (0.52) L3MBTL1ALDH1A1DGKAMAPTMAPK1
SCHEMBL17123899 0.99 ALDH1A1 (0.52) L3MBTL1ALDH1A1DGKAMAPTMAPK1
SCHEMBL17124001 0.99 ALDH1A1 (0.52) L3MBTL1ALDH1A1DGKAMAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230256098-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS BANK OF AMERICA, N.A. 2023-08-17 — — US disclosed
US-20230256098-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS BANK OF AMERICA, N.A. 2023-08-17 — — US disclosed
US-11679158-B2 Biodegradable lipids for the delivery of active agents ALNYLAM PHARMACEUTICALS, INC. (US) 2023-06-20 — — US disclosed
US-11679158-B2 Biodegradable lipids for the delivery of active agents ALNYLAM PHARMACEUTICALS, INC. (US) 2023-06-20 — — US disclosed
US-11633479-B2 Biodegradable lipids for the delivery of active agents ALNYLAM PHARMACEUTICALS, INC. (US) 2023-04-25 — — US disclosed
US-20220347302-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS ALNYLAM PHARMACEUTICALS, INC. 2022-11-03 — — US disclosed
US-20220125927-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS BANK OF AMERICA, N.A. 2022-04-28 — — US disclosed
US-11246933-B1 Biodegradable lipids for the delivery of active agents ALNYLAM PHARMACEUTICALS, INC. (US) 2022-02-15 — — US disclosed
US-11071784-B2 Biodegradable lipids for the delivery of active agents ALNYLAM PHARMACEUTICALS, INC. (US) 2021-07-27 — — US disclosed
US-10369226-B2 Biodegradable lipids for the delivery of active agents ALNYLAM PHARMACEUTICALS, INC. (US) 2019-08-06 — — US disclosed
US-20150306039-A1 IMPROVED NUCLEIC ACID LIPID PARTICLE FORMULATIONS BANK OF AMERICA, N.A. 2015-10-29 — — US disclosed
US-20150306039-A1 IMPROVED NUCLEIC ACID LIPID PARTICLE FORMULATIONS BANK OF AMERICA, N.A. 2015-10-29 — — US disclosed
US-20150273068-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS BANK OF AMERICA, N.A. 2015-10-01 — — US disclosed
US-20150273068-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS BANK OF AMERICA, N.A. 2015-10-01 — — US disclosed
US-9061063-B2 Biodegradable lipids for the delivery of active agents ALNYLAM PHARMACEUTICALS, INC. (US) 2015-06-23 — — US disclosed
US-9061063-B2 Biodegradable lipids for the delivery of active agents ALNYLAM PHARMACEUTICALS, INC. (US) 2015-06-23 — — US disclosed
WO-2014089239-A1 IMPROVED NUCLEIC ACID LIPID PARTICLE FORMULATIONS ALNYLAM PHARMACEUTICALS, INC. (US) 2014-06-12 — — WO disclosed
US-20130195920-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS ALNYLAM PHARMACEUTICALS, INC. (US) 2013-08-01 — — US disclosed
US-20130195920-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS ALNYLAM PHARMACEUTICALS, INC. (US) 2013-08-01 — — US disclosed
WO-2013086354-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS ALNYLAM PHARMACEUTICALS, INC. (US) 2013-06-13 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11633479-B2 Biodegradable lipids for the delivery of active agents LIPA, APOB, CETP L3MBTL1 1228/4885ALDH1A1 3151/4885DGKA 352/4885
US-20130195920-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS LIPA, APOB, CETP L3MBTL1 1228/4885ALDH1A1 3151/4885DGKA 352/4885
US-20150273068-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS LIPA, APOB, CETP L3MBTL1 1228/4885ALDH1A1 3151/4885DGKA 352/4885
US-10369226-B2 Biodegradable lipids for the delivery of active agents LIPA, APOB, CETP L3MBTL1 1228/4885ALDH1A1 3151/4885DGKA 352/4885
US-20220347302-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS LIPA, APOB, CETP L3MBTL1 1228/4885ALDH1A1 3151/4885DGKA 352/4885
US-11246933-B1 Biodegradable lipids for the delivery of active agents LIPA, APOB, CETP L3MBTL1 1228/4885ALDH1A1 3151/4885DGKA 352/4885
US-11679158-B2 Biodegradable lipids for the delivery of active agents LIPA, APOB, CETP L3MBTL1 1228/4885ALDH1A1 3151/4885DGKA 352/4885
US-20230256098-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS LIPA, APOB, CETP L3MBTL1 1228/4885ALDH1A1 3151/4885DGKA 352/4885
US-20220125927-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS LIPA, APOB, CETP L3MBTL1 1228/4885ALDH1A1 3151/4885DGKA 352/4885
US-11071784-B2 Biodegradable lipids for the delivery of active agents LIPA, APOB, CETP L3MBTL1 1228/4885ALDH1A1 3151/4885DGKA 352/4885
US-20150306039-A1 IMPROVED NUCLEIC ACID LIPID PARTICLE FORMULATIONS LIPA, NPC1L1, CETP L3MBTL1 1408/4885ALDH1A1 2297/4885DGKA 423/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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