SCHEMBL15027808

SCHEMBL15027808

CC(C)CCC(COC(=O)CCCCCCCCCC(CCCCCCCCCC(=O)OCC(CCC(C)C)C(C)C)OCCN1CCCC1)C(C)C

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.42
▸ L3MBTL1 Q9Y468 1/20 0.42
▸ KMT2A Q03164 2/20 0.36
▸ PRKCA P17252 3/20 0.33
▸ MAPT P10636 2/20 0.33
▸ PRKCE Q02156 1/20 0.33
▸ PRKCQ Q04759 1/20 0.33
▸ PRKCD Q05655 1/20 0.33
▸ LMNA P02545 2/20 0.33
▸ THRB P10828 2/20 0.33
▸ TSHR P16473 1/20 0.33
▸ ESR1 P03372 2/20 0.32
▸ TLR2 O60603 2/20 0.32
▸ PTPN1 P18031 1/20 0.31
▸ MEN1 O00255 1/20 0.31
▸ THRA P10827 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15027713 0.95 ALDH1A1 (0.41) ALDH1A1L3MBTL1KMT2APRKCAMAPT
SCHEMBL15027714 0.94 ALDH1A1 (0.43) ALDH1A1L3MBTL1KMT2AMAPTLMNA
SCHEMBL15027807 0.94 ALDH1A1 (0.40) ALDH1A1L3MBTL1KMT2AMAPTLMNA
SCHEMBL25989833 0.93 PAOX (0.36) ALDH1A1L3MBTL1PRKCAMAPTPRKCE
SCHEMBL25989865 0.90 ALDH1A1 (0.40) ALDH1A1L3MBTL1KMT2ATHRBMEN1
SCHEMBL15027703 0.87 ALDH1A1 (0.42) ALDH1A1L3MBTL1KMT2APRKCAMAPT
SCHEMBL15148273 0.87 PRKCA (0.41) ALDH1A1L3MBTL1PRKCAPRKCEPRKCQ
SCHEMBL15148242 0.87 PRKCA (0.41) ALDH1A1L3MBTL1PRKCAMAPTPRKCE
SCHEMBL15027750 0.86 PAOX (0.40) ALDH1A1L3MBTL1KMT2APRKCAMAPT
SCHEMBL15148243 0.86 ALDH1A1 (0.41) ALDH1A1L3MBTL1PRKCAMAPTPRKCE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230256098-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS BANK OF AMERICA, N.A. 2023-08-17 — — US disclosed
US-20230256098-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS BANK OF AMERICA, N.A. 2023-08-17 — — US disclosed
US-11679158-B2 Biodegradable lipids for the delivery of active agents ALNYLAM PHARMACEUTICALS, INC. (US) 2023-06-20 — — US disclosed
US-11679158-B2 Biodegradable lipids for the delivery of active agents ALNYLAM PHARMACEUTICALS, INC. (US) 2023-06-20 — — US disclosed
US-11633479-B2 Biodegradable lipids for the delivery of active agents ALNYLAM PHARMACEUTICALS, INC. (US) 2023-04-25 — — US disclosed
US-20220347302-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS ALNYLAM PHARMACEUTICALS, INC. 2022-11-03 — — US disclosed
US-11382979-B2 Biodegradable lipids for the delivery of active agents ALNYLAM PHARMACEUTICALS, INC. (US) 2022-07-12 — — US disclosed
US-20220175930-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS BANK OF AMERICA, N.A. 2022-06-09 — — US disclosed
US-20220175928-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS BANK OF AMERICA, N.A. 2022-06-09 — — US disclosed
US-20220175929-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS BANK OF AMERICA, N.A. 2022-06-09 — — US disclosed
US-20150306039-A1 IMPROVED NUCLEIC ACID LIPID PARTICLE FORMULATIONS BANK OF AMERICA, N.A. 2015-10-29 — — US disclosed
US-20150306039-A1 IMPROVED NUCLEIC ACID LIPID PARTICLE FORMULATIONS BANK OF AMERICA, N.A. 2015-10-29 — — US disclosed
US-20150273068-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS BANK OF AMERICA, N.A. 2015-10-01 — — US disclosed
US-20150273068-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS BANK OF AMERICA, N.A. 2015-10-01 — — US disclosed
US-9061063-B2 Biodegradable lipids for the delivery of active agents ALNYLAM PHARMACEUTICALS, INC. (US) 2015-06-23 — — US disclosed
US-9061063-B2 Biodegradable lipids for the delivery of active agents ALNYLAM PHARMACEUTICALS, INC. (US) 2015-06-23 — — US disclosed
WO-2014089239-A1 IMPROVED NUCLEIC ACID LIPID PARTICLE FORMULATIONS ALNYLAM PHARMACEUTICALS, INC. (US) 2014-06-12 — — WO disclosed
US-20130195920-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS ALNYLAM PHARMACEUTICALS, INC. (US) 2013-08-01 — — US disclosed
US-20130195920-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS ALNYLAM PHARMACEUTICALS, INC. (US) 2013-08-01 — — US disclosed
WO-2013086354-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS ALNYLAM PHARMACEUTICALS, INC. (US) 2013-06-13 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220175929-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS LIPA, APOB, CETP ALDH1A1 3151/4885L3MBTL1 1228/4885KMT2A 4005/4885
US-11633479-B2 Biodegradable lipids for the delivery of active agents LIPA, APOB, CETP ALDH1A1 3151/4885L3MBTL1 1228/4885KMT2A 4005/4885
US-20130195920-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS LIPA, APOB, CETP ALDH1A1 3151/4885L3MBTL1 1228/4885KMT2A 4005/4885
US-11382979-B2 Biodegradable lipids for the delivery of active agents LIPA, APOB, CETP ALDH1A1 3151/4885L3MBTL1 1228/4885KMT2A 4005/4885
US-20150273068-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS LIPA, APOB, CETP ALDH1A1 3151/4885L3MBTL1 1228/4885KMT2A 4005/4885
US-20220347302-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS LIPA, APOB, CETP ALDH1A1 3151/4885L3MBTL1 1228/4885KMT2A 4005/4885
US-20220175930-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS LIPA, APOB, CETP ALDH1A1 3151/4885L3MBTL1 1228/4885KMT2A 4005/4885
US-20220175928-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS LIPA, APOB, CETP ALDH1A1 3151/4885L3MBTL1 1228/4885KMT2A 4005/4885
US-11679158-B2 Biodegradable lipids for the delivery of active agents LIPA, APOB, CETP ALDH1A1 3151/4885L3MBTL1 1228/4885KMT2A 4005/4885
US-20230256098-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS LIPA, APOB, CETP ALDH1A1 3151/4885L3MBTL1 1228/4885KMT2A 4005/4885
US-20150306039-A1 IMPROVED NUCLEIC ACID LIPID PARTICLE FORMULATIONS LIPA, NPC1L1, CETP ALDH1A1 2297/4885L3MBTL1 1408/4885KMT2A 1352/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback