SCHEMBL15028259

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14680277	0.92	CA12 (0.35)	HKDC1ALDH1A1TSHRMAPK1HPGD
	SCHEMBL15028274	0.88	BCL2 (0.35)	HKDC1ALDH1A1MAPK1THRATHRB
	SCHEMBL15028275	0.85	HKDC1 (0.30)	HKDC1
	SCHEMBL14680405	0.85	ALDH1A1 (0.37)	ALDH1A1TSHRMAPK1HPGDCASP1
	SCHEMBL14680398	0.82	CYP1A2 (0.33)	ALDH1A1MAPK1HPGDHSD17B10L3MBTL1
	SCHEMBL21851697	0.80	ALDH1A1 (0.40)	CRHBPCRHR2KEAP1NFE2L2ALDH1A1
	SCHEMBL14820667	0.78	THRA (0.35)	ALDH1A1TSHRMAPK1HPGDCASP1
	SCHEMBL12449293	0.78	CYP1A2 (0.45)	HKDC1CRHBPCRHR2KEAP1NFE2L2
	SCHEMBL21889355	0.78	ALDH1A1 (0.38)	ALDH1A1TSHRMAPK1HPGDCASP1
	SCHEMBL14732734	0.78	ERBB2 (0.32)	CYP1A2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.