SCHEMBL15028262

SCHEMBL15028262

O=C1C(c2ccccc2)=C2C(=C1c1ccccc1)c1ccc(-c3ccc4c5c(cccc35)-c3ccccc3-4)c3cccc2c13

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.47
PABPC1 P11940 3/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
KDM4E B2RXH2 2/20 0.47
CYP1A2 P05177 2/20 0.43
CRHBP P24387 2/20 0.43
CRHR2 Q13324 2/20 0.43
KEAP1 Q14145 2/20 0.43
NFE2L2 Q16236 2/20 0.43
HTT P42858 4/20 0.41
LMNA P02545 3/20 0.41
KMT2A Q03164 3/20 0.41
NPSR1 Q6W5P4 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
MEN1 O00255 2/20 0.41
APAF1 O14727 1/20 0.41
NPC1 O15118 1/20 0.41
THRB P10828 1/20 0.41
XBP1 P17861 1/20 0.41
PTBP1 P26599 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14680387 0.90 PTPN1 (0.41) MAPTPABPC1SMN1; SMN2KDM4ECYP1A2
SCHEMBL22727693 0.90 MAPT (0.40) MAPTPABPC1SMN1; SMN2KDM4ECYP1A2
SCHEMBL21889361 0.89 ALDH1A1 (0.44) MAPTPABPC1SMN1; SMN2KDM4ECYP1A2
SCHEMBL75348 0.83 CYP1B1 (0.51) MAPTPABPC1KDM4ECYP1A2LMNA
SCHEMBL22143430 0.79 FGFR1 (0.55) MAPTSMN1; SMN2KDM4ECRHBPCRHR2
SCHEMBL10304455 0.79 ALDH1A1 (0.54) MAPTPABPC1KDM4ECYP1A2HTT
SCHEMBL24334669 0.79 MAPT (0.64) MAPTPABPC1SMN1; SMN2KDM4ECYP1A2
SCHEMBL21888318 0.79 CYP1B1 (0.47) MAPTPABPC1KDM4ECYP1A2LMNA
SCHEMBL75606 0.78 ALDH1A1 (0.56) MAPTPABPC1SMN1; SMN2KDM4ECRHBP
SCHEMBL29773784 0.78 ALDH1A1 (0.56) MAPTPABPC1SMN1; SMN2KDM4ECRHBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170133598-A1 NOVEL ORGANIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE, AND IMAGE DISPLAY DEVICE CANON KK (JP) 2017-05-11 US disclosed
US-20170133598-A1 NOVEL ORGANIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE, AND IMAGE DISPLAY DEVICE CANON KK (JP) 2017-05-11 US disclosed
EP-2788306-B1 NOVEL ORGANIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE, AND IMAGE DISPLAY DEVICE CANON KK (JP) 2017-05-03 EP disclosed
US-9590199-B2 Organic compound, organic light emitting device, and image display device CANON KABUSHIKI KAISHA (JP) 2017-03-07 US disclosed
US-9590199-B2 Organic compound, organic light emitting device, and image display device CANON KABUSHIKI KAISHA (JP) 2017-03-07 US disclosed
US-20140374723-A1 NOVEL ORGANIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE, AND IMAGE DISPLAY DEVICE CANON KABUSHIKI KAISHA (JP) 2014-12-25 US disclosed
US-20140374723-A1 NOVEL ORGANIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE, AND IMAGE DISPLAY DEVICE CANON KABUSHIKI KAISHA (JP) 2014-12-25 US disclosed
WO-2013084833-A1 NOVEL ORGANIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE, AND IMAGE DISPLAY DEVICE CANON KABUSHIKI KAISHA (JP) 2013-06-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170133598-A1 NOVEL ORGANIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE, AND IMAGE DISPLAY DEVICE OCIAD1, OCIAD2, OXER1 MAPT 348/4885PABPC1 3919/4885SMN1; SMN2 3481/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.