SCHEMBL10304455

SCHEMBL10304455

O=C1C(c2ccccc2)=C2C(=C1c1ccccc1)c1cc3ccccc3c3cccc2c13

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.54
HPGD P15428 2/20 0.54
CASP1 P29466 2/20 0.54
TSHR P16473 1/20 0.54
MAPK1 P28482 1/20 0.54
HIF1A Q16665 1/20 0.54
HSD17B10 Q99714 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
CES1 P23141 2/20 0.44
ALOX5 P09917 1/20 0.39
ERBB2 P04626 1/20 0.39
CYP1A2 P05177 1/20 0.39
FYN P06241 1/20 0.39
MAOA P21397 1/20 0.39
ACHE P22303 1/20 0.39
AHR P35869 1/20 0.39
PTGES O14684 1/20 0.38
CYP11B1 P15538 1/20 0.37
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10015037 0.88 ALDH1A1 (0.41) ALDH1A1HPGDCASP1TSHRMAPK1
SCHEMBL17487173 0.85 ALDH1A1 (0.45) ALDH1A1HPGDCASP1TSHRMAPK1
SCHEMBL21889361 0.85 ALDH1A1 (0.44) ALDH1A1HPGDCASP1TSHRMAPK1
SCHEMBL17490264 0.84 ALDH1A1 (0.44) ALDH1A1HPGDCASP1TSHRMAPK1
SCHEMBL14680387 0.83 PTPN1 (0.41) ALDH1A1HPGDCASP1TSHRMAPK1
SCHEMBL4979755 0.82 CES1 (0.60) ALDH1A1HPGDCASP1TSHRMAPK1
SCHEMBL29773784 0.81 ALDH1A1 (0.56) ALDH1A1HPGDCASP1TSHRMAPK1
SCHEMBL75606 0.81 ALDH1A1 (0.56) ALDH1A1HPGDCASP1TSHRMAPK1
SCHEMBL17487162 0.81 ALDH1A1 (0.58) ALDH1A1HPGDCASP1TSHRMAPK1
SCHEMBL12683614 0.79 ESR1 (0.40) ALDH1A1HPGDCASP1MAPK1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220081378-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2022-03-17 US disclosed
US-9166173-B2 Organic compound CANON KABUSHIKI KAISHA (JP) 2015-10-20 US disclosed
US-9166173-B2 Organic compound CANON KABUSHIKI KAISHA (JP) 2015-10-20 US disclosed
US-9005778-B2 Organic compound and organic light-emitting device including the same CANON KABUSHIKI KAISHA (JP) 2015-04-14 US disclosed
US-9005778-B2 Organic compound and organic light-emitting device including the same CANON KABUSHIKI KAISHA (JP) 2015-04-14 US disclosed
US-8963416-B2 Organic compound CANON KABUSHIKI KAISHA (JP) 2015-02-24 US disclosed
US-8963416-B2 Organic compound CANON KABUSHIKI KAISHA (JP) 2015-02-24 US disclosed
US-8921834-B2 Organic light-emitting device CANON KABUSHIKI KAISHA (JP) 2014-12-30 US disclosed
US-8921834-B2 Organic light-emitting device CANON KABUSHIKI KAISHA (JP) 2014-12-30 US disclosed
EP-2569268-B1 NOVEL ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CANON KK (JP) 2014-11-05 EP disclosed
WO-2011136155-A1 NOVEL ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2011-11-03 WO disclosed
US-20110260151-A1 NOVEL FUSED POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT CANON KABUSHIKI KAISHA (JP) 2011-10-27 US disclosed
US-20110260151-A1 NOVEL FUSED POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT CANON KABUSHIKI KAISHA (JP) 2011-10-27 US disclosed
US-20110251394-A1 NOVEL ORGANIC COMPOUND CANON KABUSHIKI KAISHA (JP) 2011-10-13 US disclosed
US-20110251394-A1 NOVEL ORGANIC COMPOUND CANON KABUSHIKI KAISHA (JP) 2011-10-13 US disclosed
US-20110148292-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING THE SAME CANON KABUSHIKI KAISHA (JP) 2011-06-23 US disclosed
US-20110148292-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING THE SAME CANON KABUSHIKI KAISHA (JP) 2011-06-23 US disclosed
WO-2011036868-A1 ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2011-03-31 WO disclosed
WO-2011018886-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING THE SAME CANON KABUSHIKI KAISHA (JP) 2011-02-17 WO disclosed
WO-2010071223-A1 NOVEL ORGANIC COMPOUND CANON KABUSHIKI KAISHA (JP) 2010-06-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110251394-A1 NOVEL ORGANIC COMPOUND MRPL38, RPS8, MRPS18B ALDH1A1 1113/4885HPGD 4534/4885CASP1 967/4885
US-20110148292-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING THE SAME RPS24, OR10J3, ORC3 ALDH1A1 600/4885HPGD 4094/4885CASP1 942/4885
US-20220081378-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE CCNL2, ORC3, OR51E2 ALDH1A1 1723/4885HPGD 4196/4885CASP1 1212/4885
US-20110260151-A1 NOVEL FUSED POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT INTS6, RPL6, ETV6 ALDH1A1 1058/4885HPGD 4422/4885CASP1 2097/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.