Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | TYMS | P04818 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15028262 | 0.90 | MAPT (0.47) | MAPTKDM4ESMN1; SMN2PABPC1CYP1A2 | |
| SCHEMBL22727866 | 0.86 | CYP1B1 (0.47) | MAPTKDM4EPABPC1CYP2A6TYMS | |
| SCHEMBL14680387 | 0.81 | PTPN1 (0.41) | MAPTKDM4ESMN1; SMN2PABPC1CYP1A2 | |
| SCHEMBL21889361 | 0.80 | ALDH1A1 (0.44) | MAPTKDM4ESMN1; SMN2PABPC1CYP1A2 | |
| SCHEMBL14241923 | 0.77 | CRHBP (0.52) | MAPTKDM4ESMN1; SMN2PABPC1CYP2A6 | |
| SCHEMBL75348 | 0.75 | CYP1B1 (0.51) | MAPTKDM4EPABPC1CYP1A2ALDH1A1 | |
| SCHEMBL25125279 | 0.74 | CYP2A6 (0.57) | MAPTKDM4ESMN1; SMN2CYP2A6TYMS | |
| SCHEMBL21888318 | 0.73 | CYP1B1 (0.47) | MAPTKDM4EPABPC1CYP1A2ALDH1A1 | |
| SCHEMBL16735427 | 0.71 | FGFR1 (0.55) | MAPTKDM4ESMN1; SMN2ALDH1A1POLB | |
| SCHEMBL16735433 | 0.71 | FGFR1 (0.55) | MAPTKDM4ESMN1; SMN2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200377433-A1 | ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT | CANON KABUSHIKI KAISHA (JP) | 2020-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200377433-A1 | ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT | CCNL2, MCM4, CCNT1 | MAPT 2122/4885KDM4E 1755/4885SMN1; SMN2 2896/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.