Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | PAM | P19021 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Styrene SCHEMBL11312642 | 0.91 | ALDH1A1 (0.58) | ALDH1A1TSHRHTR2ARELAIDO1 | |
| Styrene SCHEMBL5101848 | 0.91 | ALDH1A1 (0.58) | ALDH1A1TSHRHTR2ARELAIDO1 | |
| Styrene SCHEMBL27992057 | 0.89 | ALDH1A1 (0.56) | ALDH1A1TSHRHTR2ARELAIDO1 | |
| Styrene SCHEMBL28445881 | 0.87 | ALDH1A1 (0.54) | ALDH1A1TSHRHTR2ARELAIDO1 | |
| SCHEMBL659018 | 0.85 | ALDH1A1 (0.52) | ALDH1A1TSHRTDP1HTR2ARELA | |
| SCHEMBL659019 | 0.85 | ALDH1A1 (0.52) | ALDH1A1TSHRTDP1HTR2ARELA | |
| SCHEMBL5038515 | 0.85 | ALDH1A1 (0.47) | ALDH1A1TSHRMAPTTP53TDP1 | |
| Styrene SCHEMBL688121 | 0.84 | ALDH1A1 (0.50) | ALDH1A1TSHRHTR2ARELANFE2L2 | |
| SCHEMBL9861572 | 0.84 | ALDH1A1 (0.42) | ALDH1A1TSHRPPARGCYP1B1CYP3A4 | |
| Styrene SCHEMBL9583045 | 0.83 | ALDH1A1 (0.70) | ALDH1A1TSHRCYP1B1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2011510134-A | — | — | 2011-03-31 | — | — | JP | claimed |
| EP-2238201-A1 | PARTICULATE INTERPENETRATING NETWORK POLYMER | Nova Chemicals (International) S.A. (CH) | 2010-10-13 | — | — | EP | claimed |
| WO-2009091454-A1 | PARTICULATE INTERPENETRATING NETWORK POLYMER | NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) | 2009-07-23 | — | — | WO | claimed |
| US-20090181253-A1 | PARTICULATE INTERPENETRATING NETWORK POLYMER | NOVA CHEMICALS INC. (US) | 2009-07-16 | — | — | US | claimed |