Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Styrene SCHEMBL5101848 | 0.89 | ALDH1A1 (0.58) | ALDH1A1TSHRHTR2ARELAMEN1 | |
| Styrene SCHEMBL11312642 | 0.89 | ALDH1A1 (0.58) | ALDH1A1TSHRHTR2ARELAMEN1 | |
| Styrene SCHEMBL27992057 | 0.88 | ALDH1A1 (0.56) | ALDH1A1TSHRHTR2ARELAMEN1 | |
| Styrene SCHEMBL9795236 | 0.88 | ALDH1A1 (0.61) | ALDH1A1TSHRTP53CASP3SENP7 | |
| Styrene SCHEMBL28445881 | 0.86 | ALDH1A1 (0.54) | ALDH1A1TSHRHTR2ARELAMEN1 | |
| SCHEMBL1503079 | 0.85 | ALDH1A1 (0.48) | ALDH1A1TSHRTP53HTR2ARELA | |
| SCHEMBL659018 | 0.84 | ALDH1A1 (0.52) | ALDH1A1TSHRHTR2ARELATDP1 | |
| SCHEMBL9131824 | 0.84 | ALOX5 (0.50) | ALDH1A1TP53ALOX5PTGS1PTGS2 | |
| SCHEMBL9131838 | 0.84 | ALOX5 (0.50) | ALDH1A1TP53ALOX5PTGS1PTGS2 | |
| SCHEMBL659019 | 0.84 | ALDH1A1 (0.52) | ALDH1A1TSHRHTR2ARELATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7446153-B2 | Preparation of brominated styrenic polymers or resins | ALBEMARLE CORPORATION (US) | 2008-11-04 | — | — | US | disclosed |
| US-20070149718-A1 | PREPARATION OF BROMINATED STYRENIC POLYMERS OR RESINS | ALBEMARLE CORPORATION (US) | 2007-06-28 | — | — | US | disclosed |