SCHEMBL9861572

SCHEMBL9861572

C=Cc1ccc(C)cc1.CCCCC=Cc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
TSHR P16473 1/20 0.42
PDE5A O76074 1/20 0.41
SIGMAR1 Q99720 2/20 0.39
PPARG P37231 1/20 0.37
TNNC1 P63316 1/20 0.36
CYP1B1 Q16678 1/20 0.36
CYP3A4 P08684 1/20 0.36
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
TP53 P04637 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
HTR2A P28223 3/20 0.36
RELA Q04206 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL2380965 0.92 ALDH1A1 (0.50) ALDH1A1TSHRSIGMAR1TNNC1HTR2A
Styrene SCHEMBL2261497 0.91 ALDH1A1 (0.48) ALDH1A1TSHRSIGMAR1TNNC1HTR2A
Styrene SCHEMBL11565629 0.89 ALDH1A1 (0.47) ALDH1A1TSHRSIGMAR1TNNC1HTR2A
SCHEMBL657473 0.87 ALDH1A1 (0.44) ALDH1A1TSHRPDE5ATNNC1
SCHEMBL657475 0.87 ALDH1A1 (0.44) ALDH1A1TSHRPDE5ATNNC1
SCHEMBL1052313 0.85 PDE5A (0.46) PDE5ATNNC1MAPTRELA
SCHEMBL21462942 0.85 PDE5A (0.46) PDE5ATNNC1MAPTRELA
SCHEMBL1503079 0.84 ALDH1A1 (0.48) ALDH1A1TSHRPPARGCYP1B1CYP3A4
Butadiene SCHEMBL10611751 0.84 SIGMAR1 (0.45) SIGMAR1TNNC1HTR2A
Styrene SCHEMBL14058498 0.84 ALDH1A1 (0.41) ALDH1A1TSHRSIGMAR1TNNC1HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5053151-A Ethylene-alpha-olefin copolymer grafted with unsaturated carboxy compound EXXON CHEMICAL PATENTS INC. (US) 1991-10-01 US disclosed