Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15030788 | 0.85 | ALDH1A1 (0.36) | PGREGLN1 | |
| SCHEMBL15030802 | 0.79 | PDK2 (0.36) | PGR | |
| SCHEMBL17470458 | 0.78 | PDK2 (0.42) | PGRCNR1EGLN1MEN1KMT2A | |
| SCHEMBL15030713 | 0.77 | PGR (0.38) | PGRCNR1EGLN1MEN1KMT2A | |
| SCHEMBL15030712 | 0.77 | PGR (0.43) | PGRCNR1EGLN1MEN1KMT2A | |
| SCHEMBL15030714 | 0.77 | PDK2 (0.41) | PGRCNR1EGLN1MEN1KMT2A | |
| SCHEMBL16186690 | 0.76 | ADAMTS5 (0.32) | — | |
| SCHEMBL20588385 | 0.76 | PDK2 (0.40) | PGRCNR1EGLN1MEN1KMT2A | |
| SCHEMBL15030785 | 0.76 | PGR (0.40) | PGRCNR1EGLN1MEN1KMT2A | |
| SCHEMBL15030657 | 0.75 | AHR (0.41) | PGRCNR1EGLN1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2780325-B1 | SPIRO-DIHYDROACRIDINE DERIVATIVES AND THEIR USE AS MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2016-02-03 | — | — | EP | disclosed |
| US-20140316134-A1 | SPIRO DIHYDROACRIDINE DERIVATIVES AND THE USE THEREOF AS MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2014-10-23 | — | — | US | disclosed |
| US-20140316134-A1 | SPIRO DIHYDROACRIDINE DERIVATIVES AND THE USE THEREOF AS MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2014-10-23 | — | — | US | disclosed |
| WO-2013083216-A1 | SPIRO DIHYDROACRIDINE DERIVATIVES AND THE USE THEREOF AS MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2013-06-13 | — | — | WO | disclosed |