Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | EDNRB | P24530 | 1/20 | 0.30 |
| ▸ | EDNRA | P25101 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15030636 | 0.97 | L3MBTL1 (0.39) | KDM4EATML3MBTL1HDAC4 | |
| SCHEMBL15030690 | 0.91 | KDM4E (0.36) | KDM4EATML3MBTL1HDAC4 | |
| SCHEMBL15030792 | 0.91 | KDM4E (0.36) | KDM4EATML3MBTL1HDAC4EDNRB | |
| SCHEMBL15030659 | 0.89 | KDM4E (0.38) | KDM4EATML3MBTL1HDAC4EDNRB | |
| SCHEMBL16186683 | 0.89 | KDM4E (0.33) | KDM4EATML3MBTL1HDAC4 | |
| SCHEMBL19977843 | 0.88 | KDM4E (0.38) | KDM4EATML3MBTL1EDNRBEDNRA | |
| SCHEMBL19977863 | 0.88 | KDM4E (0.33) | KDM4EATML3MBTL1 | |
| SCHEMBL21037677 | 0.87 | KDM4E (0.38) | KDM4EATML3MBTL1HDAC4 | |
| SCHEMBL15030641 | 0.86 | HDAC4 (0.31) | KDM4EATML3MBTL1HDAC4 | |
| SCHEMBL15030698 | 0.86 | KDM4E (0.35) | KDM4EATML3MBTL1HDAC4EDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2780325-B1 | SPIRO-DIHYDROACRIDINE DERIVATIVES AND THEIR USE AS MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2016-02-03 | — | — | EP | disclosed |
| US-20140316134-A1 | SPIRO DIHYDROACRIDINE DERIVATIVES AND THE USE THEREOF AS MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2014-10-23 | — | — | US | disclosed |
| US-20140316134-A1 | SPIRO DIHYDROACRIDINE DERIVATIVES AND THE USE THEREOF AS MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2014-10-23 | — | — | US | disclosed |
| WO-2013083216-A1 | SPIRO DIHYDROACRIDINE DERIVATIVES AND THE USE THEREOF AS MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2013-06-13 | — | — | WO | disclosed |