Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19977904 | 0.88 | KDM4E (0.33) | KDM4EATML3MBTL1ADAMTS5 | |
| SCHEMBL19977902 | 0.88 | KDM4E (0.38) | KDM4EATML3MBTL1 | |
| SCHEMBL15030872 | 0.87 | KDM4E (0.37) | KDM4EATML3MBTL1HDAC4 | |
| SCHEMBL20696650 | 0.86 | KDM4E (0.30) | KDM4EATML3MBTL1 | |
| SCHEMBL19977876 | 0.86 | KDM4E (0.33) | KDM4EATML3MBTL1 | |
| SCHEMBL20696491 | 0.86 | L3MBTL1 (0.42) | KDM4EATML3MBTL1HDAC4ADAMTS5 | |
| SCHEMBL15030868 | 0.86 | KDM4E (0.36) | KDM4EATML3MBTL1HDAC4 | |
| SCHEMBL19977868 | 0.85 | KDM4E (0.38) | KDM4EATML3MBTL1 | |
| SCHEMBL19977908 | 0.84 | KDM4E (0.33) | KDM4EATML3MBTL1 | |
| SCHEMBL19977901 | 0.84 | KDM4E (0.35) | KDM4EATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10305040-B2 | Spiro dihydroacridine derivatives and the use thereof as materials for organic electroluminescence devices | MERCK PATENT GMBH (DE) | 2019-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10305040-B2 | Spiro dihydroacridine derivatives and the use thereof as materials for organic electroluminescence devices | SORD, ALDH1A1, SDHA | KDM4E 3566/4885ATM 2441/4885L3MBTL1 4454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.