Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | IL1R1 | P14778 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15030872 | 0.97 | KDM4E (0.37) | L3MBTL1KDM4EATMHDAC4 | |
| SCHEMBL16186683 | 0.92 | KDM4E (0.33) | L3MBTL1KDM4EATMHDAC4 | |
| SCHEMBL15030659 | 0.89 | KDM4E (0.38) | L3MBTL1KDM4EATMHDAC4 | |
| SCHEMBL15030641 | 0.89 | HDAC4 (0.31) | L3MBTL1KDM4EATMHDAC4 | |
| SCHEMBL15030690 | 0.88 | KDM4E (0.36) | L3MBTL1KDM4EATMHDAC4 | |
| SCHEMBL15030792 | 0.87 | KDM4E (0.36) | L3MBTL1KDM4EATMHDAC4 | |
| SCHEMBL15030846 | 0.86 | KDM4E (0.31) | L3MBTL1KDM4EATM | |
| SCHEMBL15030813 | 0.85 | KDM4E (0.32) | L3MBTL1KDM4EATM | |
| SCHEMBL19977863 | 0.84 | KDM4E (0.33) | L3MBTL1KDM4EATM | |
| SCHEMBL23936688 | 0.84 | L3MBTL1 (0.43) | L3MBTL1KDM4EATMHDAC4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10305040-B2 | Spiro dihydroacridine derivatives and the use thereof as materials for organic electroluminescence devices | MERCK PATENT GMBH (DE) | 2019-05-28 | — | — | US | disclosed |
| EP-2780325-B1 | SPIRO-DIHYDROACRIDINE DERIVATIVES AND THEIR USE AS MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2016-02-03 | — | — | EP | disclosed |
| US-20140316134-A1 | SPIRO DIHYDROACRIDINE DERIVATIVES AND THE USE THEREOF AS MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2014-10-23 | — | — | US | disclosed |
| US-20140316134-A1 | SPIRO DIHYDROACRIDINE DERIVATIVES AND THE USE THEREOF AS MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2014-10-23 | — | — | US | disclosed |
| WO-2013083216-A1 | SPIRO DIHYDROACRIDINE DERIVATIVES AND THE USE THEREOF AS MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2013-06-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10305040-B2 | Spiro dihydroacridine derivatives and the use thereof as materials for organic electroluminescence devices | SORD, ALDH1A1, SDHA | L3MBTL1 4454/4885KDM4E 3566/4885ATM 2441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.