Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.37 |
| ▸ | SRC | P12931 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15007021 | 0.88 | CA12 (0.36) | KMT2AMEN1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL10953413 | 0.82 | P2RX4 (0.40) | KMT2AMEN1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL21179861 | 0.81 | CA12 (0.38) | KMT2AMEN1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL9009797 | 0.80 | MAPT (0.48) | KMT2AMEN1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL9794866 | 0.79 | P2RX4 (0.49) | KMT2AMEN1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL7007991 | 0.77 | P2RX4 (0.56) | KMT2AMEN1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL18216974 | 0.77 | P2RX4 (0.36) | KMT2AMEN1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL11303496 | 0.76 | P2RX4 (0.43) | KMT2AMEN1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL10485311 | 0.76 | P2RX4 (0.54) | KMT2AMEN1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL10955890 | 0.75 | P2RX4 (0.40) | KMT2AMEN1ALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10357574-B2 | Optical sensor conjugates for detecting reactive oxygen and/or reactive nitrogen species in vivo | THE GENERAL HOSPITAL CORPORATION (US) | 2019-07-23 | — | — | US | disclosed |
| US-20170368202-A1 | OPTICAL SENSOR CONJUGATES FOR DETECTING REACTIVE OXYGEN AND/OR REACTIVE NITROGEN SPECIES IN VIVO | THE GENERAL HOSPITAL CORPORATION | 2017-12-28 | — | — | US | disclosed |
| US-9636423-B2 | Optical sensor conjugates for detecting reactive oxygen and/or reactive nitrogen species in vivo | THE GENERAL HOSPITAL CORPORATION (US) | 2017-05-02 | — | — | US | disclosed |
| US-9636423-B2 | Optical sensor conjugates for detecting reactive oxygen and/or reactive nitrogen species in vivo | THE GENERAL HOSPITAL CORPORATION (US) | 2017-05-02 | — | — | US | disclosed |
| US-20130149251-A1 | OPTICAL SENSOR CONJUGATES FOR DETECTING REACTIVE OXYGEN AND/OR REACTIVE NITROGEN SPECIES IN VIVO | THE GENERAL HOSPITAL CORPORATION (US) | 2013-06-13 | — | — | US | disclosed |
| US-20130149251-A1 | OPTICAL SENSOR CONJUGATES FOR DETECTING REACTIVE OXYGEN AND/OR REACTIVE NITROGEN SPECIES IN VIVO | THE GENERAL HOSPITAL CORPORATION (US) | 2013-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170368202-A1 | OPTICAL SENSOR CONJUGATES FOR DETECTING REACTIVE OXYGEN AND/OR REACTIVE NITROGEN SPECIES IN VIVO | MPO, NOX3, CYBB | KMT2A 4048/4885MEN1 3881/4885ALDH1A1 2334/4885 |
| US-20130149251-A1 | OPTICAL SENSOR CONJUGATES FOR DETECTING REACTIVE OXYGEN AND/OR REACTIVE NITROGEN SPECIES IN VIVO | MPO, NOX3, CYBB | KMT2A 4048/4885MEN1 3881/4885ALDH1A1 2334/4885 |
| US-10357574-B2 | Optical sensor conjugates for detecting reactive oxygen and/or reactive nitrogen species in vivo | MPO, NOX3, CYBB | KMT2A 4048/4885MEN1 3881/4885ALDH1A1 2334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.