Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15031940 | 0.93 | CA12 (0.36) | CA12CA9KMT2ANPC1RAB9A | |
| SCHEMBL15031932 | 0.81 | KMT2A (0.38) | CA12CA9KMT2ANPC1RAB9A | |
| SCHEMBL15007021 | 0.79 | CA12 (0.36) | CA12CA9KMT2ANPC1RAB9A | |
| SCHEMBL15006732 | 0.76 | MAPK1 (0.46) | KMT2ANPC1MAPTALDH1A1LMNA | |
| SCHEMBL583642 | 0.73 | HDAC3 (0.55) | KMT2ANPC1RAB9APOLBMAPT | |
| SCHEMBL10953413 | 0.73 | P2RX4 (0.40) | CA12CA9KMT2ANPC1RAB9A | |
| SCHEMBL9009797 | 0.71 | MAPT (0.48) | CA12CA9KMT2APOLBP2RX4 | |
| SCHEMBL10485311 | 0.71 | P2RX4 (0.54) | CA12CA9KMT2ANPC1RAB9A | |
| SCHEMBL29625793 | 0.70 | P2RX4 (0.49) | CA12CA9KMT2AP2RX4MAPT | |
| SCHEMBL15031938 | 0.70 | MAPK1 (0.42) | KMT2AMAPTALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10357574-B2 | Optical sensor conjugates for detecting reactive oxygen and/or reactive nitrogen species in vivo | THE GENERAL HOSPITAL CORPORATION (US) | 2019-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10357574-B2 | Optical sensor conjugates for detecting reactive oxygen and/or reactive nitrogen species in vivo | MPO, NOX3, CYBB | CA12 403/4885CA9 177/4885KMT2A 4048/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.