Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15006732 | 0.93 | MAPK1 (0.46) | MAPK1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL15031940 | 0.78 | CA12 (0.36) | KMT2A | |
| SCHEMBL15031934 | 0.76 | MAPK1 (0.59) | MAPK1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL15007308 | 0.74 | MAPK1 (0.53) | MAPK1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL15308992 | 0.73 | KMT2A (0.33) | KMT2A | |
| SCHEMBL21179861 | 0.70 | CA12 (0.38) | MAPK1MEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL19432859 | 0.69 | KMT2A (0.32) | KMT2A | |
| SCHEMBL11764947 | 0.69 | MAPK1 (0.62) | MAPK1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL13019549 | 0.69 | MAPK1 (0.50) | MAPK1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL16938161 | 0.68 | KMT2A (0.41) | KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170368202-A1 | OPTICAL SENSOR CONJUGATES FOR DETECTING REACTIVE OXYGEN AND/OR REACTIVE NITROGEN SPECIES IN VIVO | THE GENERAL HOSPITAL CORPORATION | 2017-12-28 | — | — | US | disclosed |
| US-20130149251-A1 | OPTICAL SENSOR CONJUGATES FOR DETECTING REACTIVE OXYGEN AND/OR REACTIVE NITROGEN SPECIES IN VIVO | THE GENERAL HOSPITAL CORPORATION (US) | 2013-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170368202-A1 | OPTICAL SENSOR CONJUGATES FOR DETECTING REACTIVE OXYGEN AND/OR REACTIVE NITROGEN SPECIES IN VIVO | MPO, NOX3, CYBB | MAPK1 1531/4885MEN1 3881/4885KMT2A 4048/4885 |
| US-20130149251-A1 | OPTICAL SENSOR CONJUGATES FOR DETECTING REACTIVE OXYGEN AND/OR REACTIVE NITROGEN SPECIES IN VIVO | MPO, NOX3, CYBB | MAPK1 1531/4885MEN1 3881/4885KMT2A 4048/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.