SCHEMBL1503202

SCHEMBL1503202

NC(F)c1ccccc1F

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 3/20 0.45
TDO2 P48775 2/20 0.45
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
GAA P10253 2/20 0.40
CYP3A4 P08684 2/20 0.36
MEN1 O00255 1/20 0.36
ALDH1A1 P00352 1/20 0.36
MAPT P10636 1/20 0.36
CYP2C9 P11712 1/20 0.36
KMT2A Q03164 1/20 0.36
ACHE P22303 1/20 0.36
TAAR1 Q96RJ0 1/20 0.36
CNR2 P34972 1/20 0.35
MGAM O43451 1/20 0.35
SI P14410 1/20 0.35
MGAM2 Q2M2H8 1/20 0.35
NFE2L2 Q16236 1/20 0.35
OPRM1 P35372 1/20 0.33
OPRD1 P41143 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3254677 0.81 IDO1 (0.47) IDO1TDO2CES2CES1GAA
SCHEMBL3256063 0.81 IDO1 (0.47) IDO1TDO2CES2CES1GAA
SCHEMBL17842404 0.81 IDO1 (0.47) IDO1TDO2CES2CES1GAA
SCHEMBL3675762 0.81 IDO1 (0.47) IDO1TDO2CES2CES1GAA
SCHEMBL12568801 0.81 IDO1 (0.47) IDO1TDO2CES2CES1GAA
SCHEMBL18449599 0.80 IDO1 (0.42) IDO1TDO2CES2CES1GAA
SCHEMBL6824093 0.80 CES2 (0.44) IDO1TDO2CES2CES1GAA
SCHEMBL30682740 0.80 IDO1 (0.42) IDO1TDO2CES2CES1GAA
SCHEMBL1999868 0.78 IDO1 (0.43) IDO1TDO2CES2CES1GAA
SCHEMBL29768740 0.78 IDO1 (0.43) IDO1TDO2CES2CES1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12337036-B2 Compounds and methods for trans-membrane delivery of molecules APOSENSE LTD (IL) 2025-06-24 US claimed
CN-114369070-B Preparation process of rufinamide 海南医学院 2023-04-14 CN claimed
CN-114369070-A Preparation process of rufinamide 海南医学院 2022-04-19 CN claimed
CN-215440287-U Post-treatment device for difluorobenzylamine and trifluorobenzylamine 弈柯莱(台州)药业有限公司 2022-01-07 CN claimed
US-20210052736-A1 COMPOUNDS AND METHODS FOR TRANS-MEMBRANE DELIVERY OF MOLECULES APOSENSE LTD (IL) 2021-02-25 US claimed
EP-3735276-A1 COMPOUNDS AND METHODS FOR TRANS-MEMBRANE DELIVERY OF MOLECULES Aposense Ltd. (IL) 2020-11-11 EP claimed
CN-111615404-A Compounds and methods for transmembrane delivery of molecules 艾博森斯有限公司 2020-09-01 CN claimed
US-12337036-B2 Compounds and methods for trans-membrane delivery of molecules APOSENSE LTD (IL) 2025-06-24 US disclosed
CN-117327091-A Synthesis method of Rayleigh Lu Geli 浙江天宇药业股份有限公司 2024-01-02 CN disclosed
CN-116826293-A Battery top cover and battery pack and vehicle with battery top cover 中国第一汽车股份有限公司 2023-09-29 CN disclosed
CN-116419937-A Composition for forming resist underlayer film 日产化学株式会社 2023-07-11 CN disclosed
CN-114369070-B Preparation process of rufinamide 海南医学院 2023-04-14 CN disclosed
CN-114369070-B Preparation process of rufinamide 海南医学院 2023-04-14 CN disclosed
EP-1392317-A2 SUBSTITUTED 1-BENZAZEPINES AND DERIVATIVES THEREOF Antexpharma, Inc. (US) 2004-03-03 EP disclosed
WO-2003051897-A1 NUCLEOSIDE ANALOG LIBRARIES AND COMPOUNDS RIBAPHARM INC. (US) 2003-06-26 WO disclosed
WO-2003004027-A1 SUBSTITUTED ANILINIC PIPERIDINES AS MCH SELECTIVE ANTAGONISTS SYNAPTIC PHARMACEUTICAL CORPORATION (US) 2003-01-16 WO disclosed
WO-2002100327-A2 SUBSTITUTED 1-BENZAZEPINES AND DERIVATIVES THEREOF ANTEXPHARMA, INC. (US) 2002-12-19 WO disclosed
EP-1220842-A1 CYCLIC AMINE COMPOUNDS AS CCR5 ANTAGONISTS Takeda Chemical Industries, Ltd. (JP) 2002-07-10 EP disclosed
WO-2001025200-A1 CYCLIC AMINE COMPOUNDS AS CCR5 ANTAGONISTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2001-04-12 WO disclosed
EP-0427445-A1 Benzylideneaminoxyalkanoic acid (thio) amide derivative, process for preparing the same and herbicide UBE INDUSTRIES, LTD. (JP) 1991-05-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12337036-B2 Compounds and methods for trans-membrane delivery of molecules LDLR, NPC1L1, ABCB4 IDO1 4861/4885TDO2 4652/4885CES2 516/4885
US-20210052736-A1 COMPOUNDS AND METHODS FOR TRANS-MEMBRANE DELIVERY OF MOLECULES LDLR, NPC1L1, ABCB4 IDO1 4861/4885TDO2 4652/4885CES2 516/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.