Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | TDO2 | P48775 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 2/20 | 0.43 |
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29768740 | 1.00 | IDO1 (0.43) | IDO1TDO2CES2CES1ACHE | |
| SCHEMBL1538924 | 0.81 | GABRA1 (0.35) | IDO1TDO2CES2CES1KCNN4 | |
| SCHEMBL2066940 | 0.79 | IDO1 (0.45) | IDO1TDO2CES2CES1ACHE | |
| SCHEMBL28823241 | 0.78 | IDO1 (0.41) | IDO1TDO2CES2CES1ACHE | |
| SCHEMBL1503202 | 0.78 | IDO1 (0.45) | IDO1TDO2CES2CES1ACHE | |
| SCHEMBL536229 | 0.78 | CES2 (0.50) | IDO1TDO2CES2CES1ACHE | |
| SCHEMBL127093 | 0.78 | IDO1 (0.41) | IDO1TDO2CES2CES1ACHE | |
| SCHEMBL16956757 | 0.78 | CES2 (0.47) | IDO1TDO2CES2CES1ACHE | |
| SCHEMBL4219819 | 0.78 | IDO1 (0.41) | IDO1TDO2CES2CES1ACHE | |
| SCHEMBL11602791 | 0.77 | CES2 (0.54) | IDO1TDO2CES2CES1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115819251-B | Preparation method of (1R) -1- [3- (difluoromethyl) -2-fluorophenyl ] ethylamine | 沧州普瑞东方科技有限公司 | 2024-04-09 | — | — | CN | claimed |
| CN-115819251-A | Preparation method of (1R) -1- [3- (difluoromethyl) -2-fluorophenyl ] ethylamine | 沧州普瑞东方科技有限公司 | 2023-03-21 | — | — | CN | claimed |
| US-8952083-B2 | Fluorocopolymer composition and its production process | ASAHI GLASS COMPANY, LIMITED (JP) | 2015-02-10 | — | — | US | claimed |
| CN-111732569-B | Liquid crystalline compound having dibenzothiophene ring, liquid crystal composition, and liquid crystal display element | 捷恩智株式会社 | 2024-07-09 | — | — | CN | disclosed |
| CN-115819251-B | Preparation method of (1R) -1- [3- (difluoromethyl) -2-fluorophenyl ] ethylamine | 沧州普瑞东方科技有限公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-115819251-B | Preparation method of (1R) -1- [3- (difluoromethyl) -2-fluorophenyl ] ethylamine | 沧州普瑞东方科技有限公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-117263781-A | Compound, liquid crystal composition and liquid crystal display element | 捷恩智株式会社 | 2023-12-22 | — | — | CN | disclosed |
| US-20230399342-A1 | TRICYCLIC TRIAZOLO COMPOUNDS AS DGK INHIBITORS | INCYTE CORPORATION | 2023-12-14 | — | — | US | disclosed |
| CN-110300746-B | Liquid crystalline compound, liquid crystal composition, and liquid crystal display element | 捷恩智株式会社 | 2023-08-15 | — | — | CN | disclosed |
| CN-115819251-A | Preparation method of (1R) -1- [3- (difluoromethyl) -2-fluorophenyl ] ethylamine | 沧州普瑞东方科技有限公司 | 2023-03-21 | — | — | CN | disclosed |
| CN-115819251-A | Preparation method of (1R) -1- [3- (difluoromethyl) -2-fluorophenyl ] ethylamine | 沧州普瑞东方科技有限公司 | 2023-03-21 | — | — | CN | disclosed |
| US-7247355-B2 | Liquid crystal compound having chroman ring, liquid crystal composition comprising the compound and liquid crystal display device comprising the composition | CHISSO CORPORATION (JP) | 2007-07-24 | — | — | US | disclosed |
| EP-1674550-A1 | Liquid crystal compound having chroman ring, liquid crystal composition comprising the compound and liquid crystal display device comprising the composition | CHISSO CORPORATION (JP) | 2006-06-28 | — | — | EP | disclosed |
| US-20060131540-A1 | Liquid crystal compound having chroman ring, liquid crystal composition comprising the compound and liquid crystal display device comprising the composition | JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) | 2006-06-22 | — | — | US | disclosed |
| US-20050107609-A1 | Pyrimidine compounds and their use | SUMITOMO CHEMICAL COMPANY | 2005-05-19 | — | — | US | disclosed |
| EP-1366026-B1 | PYRIMIDINE COMPOUNDS AND THEIR USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2004-12-01 | — | — | EP | disclosed |
| EP-1088221-A4 | METHOD OF RESOLVING ANALYTES IN A FLUID | CALIFORNIA INST OF TECHN (US) | 2001-12-12 | — | — | EP | disclosed |
| EP-1088221-A1 | METHOD OF RESOLVING ANALYTES IN A FLUID | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2001-04-04 | — | — | EP | disclosed |
| WO-1999061902-A1 | METHOD OF RESOLVING ANALYTES IN A FLUID | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1999-12-02 | — | — | WO | disclosed |
| CN-1037058-C | Herbicide composition and use thereof | RHONE POULENC AGRICULTURE (GB) | 1998-01-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107609-A1 | Pyrimidine compounds and their use | TYMP, TYMS, UMPS | IDO1 1097/4885TDO2 1011/4885CES2 2005/4885 |
| US-20230399342-A1 | TRICYCLIC TRIAZOLO COMPOUNDS AS DGK INHIBITORS | DGKA, DGKI, DGKG | IDO1 4255/4885TDO2 2353/4885CES2 1570/4885 |
| US-20060131540-A1 | Liquid crystal compound having chroman ring, liquid crystal composition comprising the compound and liquid crystal display device comprising the composition | CFH, RCC1, RCC2 | IDO1 2403/4885TDO2 804/4885CES2 3269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.