Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.44 |
| ▸ | HTT | P42858 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15032179 | 0.79 | KDM4E (0.50) | KDM4EHTTLMNAGAAMAPT | |
| SCHEMBL4411512 | 0.75 | KDM5A (0.60) | KDM5AKDM4EHTTLMNAGAA | |
| SCHEMBL23388826 | 0.75 | SMN1; SMN2 (0.61) | KDM5AKDM4EHTTLMNAGAA | |
| SCHEMBL29995352 | 0.75 | SMN1; SMN2 (0.61) | KDM5AKDM4EHTTLMNAGAA | |
| SCHEMBL1147702 | 0.71 | KDM4E (0.73) | KDM5AKDM4EHTTLMNAOPRK1 | |
| SCHEMBL28871817 | 0.69 | KDM5A (0.63) | KDM5AKDM4EHTTLMNAOPRK1 | |
| SCHEMBL4404069 | 0.67 | TLR7 (0.51) | KDM5AKDM4EHTTLMNAGAA | |
| SCHEMBL4404076 | 0.66 | TLR7 (0.60) | KDM5AKDM4EHTTLMNAGAA | |
| SCHEMBL1412816 | 0.66 | CES2 (0.61) | KDM4EHTTLMNAGAAMAPT | |
| SCHEMBL28871787 | 0.65 | TLR7 (0.69) | KDM5AKDM4EHTTLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130150358-A1 | THERAMUTEIN MODULATORS | HMI MEDICAL INNOVATIONS, LLC. (US) | 2013-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130150358-A1 | THERAMUTEIN MODULATORS | TSG101, SERPINE1, PLAUR | KDM5A 4434/4885KDM4E 4221/4885HTT 1926/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.