Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 3/20 | 0.36 |
| ▸ | CDK2 | P24941 | 3/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1503148 | 0.89 | RAB9A (0.44) | CCNA2CDK2CCNA1KMT2ANPC1 | |
| SCHEMBL1503137 | 0.85 | CYP1A2 (0.44) | CCNA2CDK2KMT2ANPC1RAB9A | |
| SCHEMBL1503192 | 0.83 | ALDH1A1 (0.40) | CCNA2CDK2CCNA1MAOBKMT2A | |
| SCHEMBL2146752 | 0.80 | HSD11B1 (0.35) | MAOBKMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL2147314 | 0.80 | ALDH1A1 (0.41) | MAOBKMT2ANPC1RAB9AMAPT | |
| SCHEMBL1503189 | 0.79 | KMT2A (0.40) | MAOBKMT2AMAPTMEN1MAPK1 | |
| SCHEMBL30193078 | 0.79 | KMT2A (0.40) | MAOBKMT2AMAPTMEN1MAPK1 | |
| SCHEMBL2146827 | 0.78 | HSD11B1 (0.34) | MAOBKMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL12444456 | 0.77 | MAPT (0.47) | KMT2AMAPTMEN1MAPK1ALDH1A1 | |
| SCHEMBL12444452 | 0.76 | HDAC3 (0.36) | MAOBKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300433-A1 | HIV INTEGRASE INHIBITORS FROM PYRIDOXINE | Ambrilia Biopharma Inc. (CA) | 2011-03-30 | — | — | EP | disclosed |
| WO-2009146555-A1 | HIV INTEGRASE INHIBITORS FROM PYRIDOXINE | AMBRILIA BIOPHARMA INC. (CA) | 2009-12-10 | — | — | WO | disclosed |