Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16132592 | 0.90 | THRB (0.41) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL15032908 | 0.81 | TSHR (0.49) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL42001 | 0.79 | THRB (0.52) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL3048625 | 0.79 | THRB (0.49) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL15032662 | 0.78 | TSHR (0.37) | THRBTSHRALDH1A1TDP1FOLH1 | |
| SCHEMBL15032664 | 0.78 | TSHR (0.47) | THRBTSHRALDH1A1FOLH1 | |
| Ethylene SCHEMBL28716890 | 0.78 | THRB (0.50) | THRBTSHRALDH1A1POLBAPEX1 | |
| Phosphoric Acid SCHEMBL836840 | 0.77 | THRB (0.63) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL3048627 | 0.77 | THRB (0.59) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL14044625 | 0.76 | THRB (0.58) | THRBTSHRALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9040602-B2 | Dental materials on the basis of highly acidic polymerizable bisphosphonic acids | IVOCLAR VIVADENT AG (LI) | 2015-05-26 | — | — | US | disclosed |
| US-9040602-B2 | Dental materials on the basis of highly acidic polymerizable bisphosphonic acids | IVOCLAR VIVADENT AG (LI) | 2015-05-26 | — | — | US | disclosed |
| US-20140296364-A1 | Dental Materials on the Basis of Highly Acidic Polymerizable Bisphosphonic Acids | IVOCLAR VIVADENT AG (LI) | 2014-10-02 | — | — | US | disclosed |
| US-20140296364-A1 | Dental Materials on the Basis of Highly Acidic Polymerizable Bisphosphonic Acids | IVOCLAR VIVADENT AG (LI) | 2014-10-02 | — | — | US | disclosed |
| WO-2013083734-A1 | DENTAL MATERIALS ON THE BASIS OF HIGHLY ACIDIC POLYMERISABLE BISPHOSPHONIC ACIDS | IVOCLAR VIVADENT AG (LI) | 2013-06-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140296364-A1 | Dental Materials on the Basis of Highly Acidic Polymerizable Bisphosphonic Acids | PHOSPHO1, PTK2, ITGA1 | THRB 3994/4885TSHR 4440/4885ALDH1A1 1291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.