Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 2/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 4/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16132592 | 0.92 | THRB (0.41) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL16026753 | 0.87 | TSHR (0.62) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL12504621 | 0.87 | TSHR (0.62) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL28304257 | 0.87 | TSHR (0.62) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL12504625 | 0.87 | TSHR (0.62) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL15389725 | 0.87 | TSHR (0.62) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL2943884 | 0.87 | TSHR (0.62) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL15389940 | 0.87 | TSHR (0.62) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL719879 | 0.87 | TSHR (0.62) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL15390027 | 0.87 | TSHR (0.62) | TSHRTDP1POLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9040602-B2 | Dental materials on the basis of highly acidic polymerizable bisphosphonic acids | IVOCLAR VIVADENT AG (LI) | 2015-05-26 | — | — | US | disclosed |
| US-9040602-B2 | Dental materials on the basis of highly acidic polymerizable bisphosphonic acids | IVOCLAR VIVADENT AG (LI) | 2015-05-26 | — | — | US | disclosed |
| US-20140296364-A1 | Dental Materials on the Basis of Highly Acidic Polymerizable Bisphosphonic Acids | IVOCLAR VIVADENT AG (LI) | 2014-10-02 | — | — | US | disclosed |
| US-20140296364-A1 | Dental Materials on the Basis of Highly Acidic Polymerizable Bisphosphonic Acids | IVOCLAR VIVADENT AG (LI) | 2014-10-02 | — | — | US | disclosed |
| WO-2013083734-A1 | DENTAL MATERIALS ON THE BASIS OF HIGHLY ACIDIC POLYMERISABLE BISPHOSPHONIC ACIDS | IVOCLAR VIVADENT AG (LI) | 2013-06-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140296364-A1 | Dental Materials on the Basis of Highly Acidic Polymerizable Bisphosphonic Acids | PHOSPHO1, PTK2, ITGA1 | TSHR 4440/4885TDP1 3305/4885POLB 2534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.