Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.44 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TYMS | P04818 | 1/20 | 0.38 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15389725 | 1.00 | TSHR (0.62) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL15390027 | 1.00 | TSHR (0.62) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL28304257 | 1.00 | TSHR (0.62) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL15389940 | 1.00 | TSHR (0.62) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL12504625 | 1.00 | TSHR (0.62) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL16026753 | 1.00 | TSHR (0.62) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL12504621 | 1.00 | TSHR (0.62) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL2943884 | 1.00 | TSHR (0.62) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL31091779 | 0.98 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL294789 | 0.98 | TSHR (0.59) | TSHRPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3848418-B1 | DENTAL CURABLE COMPOSITION AND METHOD FOR PRODUCING DENTAL CURABLE COMPOSITION | TOKUYAMA DENTAL CORP (JP) | 2024-05-22 | — | — | EP | disclosed |
| US-20220169844-A1 | COMPOSITE PARTICLES, KIT, MATERIAL, AND METHOD FOR PRODUCING COMPOSITE PARTICLES | SUN MEDICAL CO., LTD. (JP) | 2022-06-02 | — | — | US | disclosed |
| EP-3415539-B1 | POLYMERIZABLE COMPOSITION AND KIT THEREOF, AND POLYMERIZATION INITIATOR | SUN MEDICAL CO LTD (JP) | 2022-03-30 | — | — | EP | disclosed |
| CN-109890343-B | Curable composition | 株式会社德山齿科 | 2022-01-04 | — | — | CN | disclosed |
| EP-3613779-B1 | CURABLE COMPOSITION | TOKUYAMA DENTAL CORP (JP) | 2021-11-24 | — | — | EP | disclosed |
| US-20210324178-A1 | COMPOSITE MATERIAL, CURABLE COMPOSITION, AND METHOD FOR PRODUCING CURABLE COMPOSITION | TOKUYAMA DENTAL CORPORATION (JP) | 2021-10-21 | — | — | US | disclosed |
| US-11130864-B2 | Polymerizable composition and kit, and polymerization initiator | SUN MEDICAL CO., LTD. (JP) | 2021-09-28 | — | — | US | disclosed |
| CN-108024913-B | Curable composition, curable composition for dentistry, and organic-inorganic composite particle for dentistry | 德山齿科株式会社 | 2021-08-10 | — | — | CN | disclosed |
| CN-110431156-B | Curable composition | 株式会社德山齿科 | 2021-08-06 | — | — | CN | disclosed |
| US-11078303-B2 | Curable composition | TOKUYAMA DENTAL CORPORATION (JP) | 2021-08-03 | — | — | US | disclosed |
| US-7776936-B2 | One-pack type dental adhesive composition | KABUSHIKI KAISHA SHOFU (JP) | 2010-08-17 | — | — | US | disclosed |
| US-7683103-B2 | Dental polymerizable composition | KURARAY MEDICAL INC. (JP) | 2010-03-23 | — | — | US | disclosed |
| US-20100069524-A1 | Single-Component dental composition containing silane coupling agent and acidic group-containing polymerizable monomer | KABUSHIKI KAISHA SHOFU | 2010-03-18 | — | — | US | disclosed |
| US-20090076182-A1 | One-pack type dental adhesive composition | KABUSHIKI KAISHA SHOFU (JP) | 2009-03-19 | — | — | US | disclosed |
| EP-2036532-A2 | One pack type dental adhesive composition | Kabushiki Kaisha Shofu (JP) | 2009-03-18 | — | — | EP | disclosed |
| US-20080039592-A1 | Dental Polymerizable Composition | KURARAY MEDICAL INC. (JP) | 2008-02-14 | — | — | US | disclosed |
| EP-1787623-A1 | DENTAL POLYMERIZABLE COMPOSITION | Kuraray Medical Inc. (JP) | 2007-05-23 | — | — | EP | disclosed |
| US-6939901-B2 | Adhesive composition | KURARAY MEDICAL, INC. (JP) | 2005-09-06 | — | — | US | disclosed |
| US-20020198284-A1 | Adhesive composition | KURARAY CO. LTD, (JP) | 2002-12-26 | — | — | US | disclosed |
| EP-1262530-A1 | ADHESIVE COMPOSITION | KURARAY CO., LTD. (JP) | 2002-12-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069524-A1 | Single-Component dental composition containing silane coupling agent and acidic group-containing polymerizable monomer | CAD, ITGA1, CIB1 | TSHR 4642/4885POLB 3832/4885APEX1 2551/4885 |
| US-11130864-B2 | Polymerizable composition and kit, and polymerization initiator | KIT, MCM7, EPHA7 | TSHR 4807/4885POLB 64/4885APEX1 4317/4885 |
| US-20090076182-A1 | One-pack type dental adhesive composition | DSC1, ITGA1, CAD | TSHR 4689/4885POLB 3491/4885APEX1 1322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.