Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 9/20 | 0.59 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.56 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.56 |
| ▸ | FAAH | O00519 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CCR6 | P51684 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8542401 | 0.89 | MGLL (0.62) | MGLLCACNA1BAPBA1FAAHALDH1A1 | |
| SCHEMBL8526538 | 0.89 | MGLL (0.62) | MGLLCACNA1BAPBA1FAAHALDH1A1 | |
| SCHEMBL3003422 | 0.88 | MGLL (0.62) | MGLLFAAHHTTLMNATP53 | |
| SCHEMBL2997957 | 0.88 | MGLL (0.62) | MGLLFAAHHTTLMNATP53 | |
| SCHEMBL3668333 | 0.87 | MGLL (0.60) | MGLLCACNA1BAPBA1FAAHALDH1A1 | |
| SCHEMBL3676454 | 0.85 | LMNA (0.66) | MGLLCACNA1BAPBA1FAAHALDH1A1 | |
| SCHEMBL10297378 | 0.84 | MGLL (0.62) | MGLLCACNA1BAPBA1FAAHALDH1A1 | |
| SCHEMBL18840331 | 0.84 | MGLL (0.56) | MGLLCACNA1BAPBA1FAAHALDH1A1 | |
| SCHEMBL8528761 | 0.84 | MGLL (0.56) | MGLLCACNA1BAPBA1FAAHALDH1A1 | |
| SCHEMBL28773523 | 0.82 | MGLL (0.55) | MGLLCACNA1BAPBA1FAAHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109593154-B | Selenium-containing maleimide polymer and preparation method and application thereof | 苏州大学 | 2021-03-12 | — | — | CN | claimed |
| CN-109593154-B | Selenium-containing maleimide polymer and preparation method and application thereof | 苏州大学 | 2021-03-12 | — | — | CN | disclosed |
| US-20130156795-A1 | METHODS FOR INHIBITION OF CELL PROLIFERATION, SYNERGISTIC TRANSCRIPTION MODULES AND USES THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2013-06-20 | — | — | US | disclosed |
| US-20130156795-A1 | METHODS FOR INHIBITION OF CELL PROLIFERATION, SYNERGISTIC TRANSCRIPTION MODULES AND USES THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2013-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130156795-A1 | METHODS FOR INHIBITION OF CELL PROLIFERATION, SYNERGISTIC TRANSCRIPTION MODULES AND USES THEREOF | MKI67, DCX, CTCF | MGLL 4517/4885CACNA1B 4128/4885APBA1 2216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.