SCHEMBL18840331

SCHEMBL18840331

O=C1C=CC(=O)N1c1ccc(OCCOCCOc2ccc(N3C(=O)C=CC3=O)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 16/20 0.56
FAAH O00519 5/20 0.56
HSP90AA1 P07900 3/20 0.51
PKM P14618 2/20 0.51
ALDH1A1 P00352 2/20 0.51
HPGD P15428 2/20 0.51
HTT P42858 2/20 0.51
MEN1 O00255 1/20 0.51
LMNA P02545 1/20 0.51
CCR6 P51684 1/20 0.51
KMT2A Q03164 1/20 0.51
ATM Q13315 1/20 0.51
NPSR1 Q6W5P4 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
MAPK1 P28482 1/20 0.47
DDAH1 O94760 1/20 0.43
CACNA1B Q00975 1/20 0.42
APBA1 Q02410 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8528761 1.00 MGLL (0.56) MGLLFAAHHSP90AA1PKMALDH1A1
SCHEMBL8542401 0.94 MGLL (0.62) MGLLFAAHHSP90AA1PKMALDH1A1
SCHEMBL8526538 0.94 MGLL (0.62) MGLLFAAHHSP90AA1PKMALDH1A1
SCHEMBL14380339 0.92 MGLL (0.57) MGLLFAAHHSP90AA1PKMALDH1A1
SCHEMBL11932953 0.92 MGLL (0.57) MGLLFAAHHSP90AA1PKMALDH1A1
SCHEMBL3668333 0.89 MGLL (0.60) MGLLFAAHHSP90AA1PKMALDH1A1
SCHEMBL10297378 0.86 MGLL (0.62) MGLLFAAHHSP90AA1PKMALDH1A1
SCHEMBL14380338 0.85 MGLL (0.43) MGLLFAAHHSP90AA1PKMALDH1A1
SCHEMBL15033477 0.84 MGLL (0.59) MGLLFAAHHSP90AA1PKMALDH1A1
SCHEMBL28773523 0.84 MGLL (0.55) MGLLFAAHHSP90AA1PKMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170135344-A1 BUILT-IN ANTIMICROBIAL PLASTIC RESINS AND METHODS FOR MAKING THE SAME NANO AND ADVANCED MATERIALS INSTITUTE LIMITED (HK) 2017-05-18 US disclosed
US-20170135344-A1 BUILT-IN ANTIMICROBIAL PLASTIC RESINS AND METHODS FOR MAKING THE SAME NANO AND ADVANCED MATERIALS INSTITUTE LIMITED (HK) 2017-05-18 US disclosed
US-20170129139-A1 BUILT-IN ANTIMICROBIAL PLASTIC RESINS AND METHODS FOR MAKING THE SAME NANO AND ADVANCED MATERIALS INSTITUTE LIMITED (HK) 2017-05-11 US disclosed
US-20170129139-A1 BUILT-IN ANTIMICROBIAL PLASTIC RESINS AND METHODS FOR MAKING THE SAME NANO AND ADVANCED MATERIALS INSTITUTE LIMITED (HK) 2017-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170135344-A1 BUILT-IN ANTIMICROBIAL PLASTIC RESINS AND METHODS FOR MAKING THE SAME PUF60, CUTA, MFAP1 MGLL 633/4885FAAH 2577/4885HSP90AA1 1386/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.