Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | HPGD | P15428 | 5/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.55 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.55 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | CCR6 | P51684 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | MGLL | Q99685 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11357026 | 0.87 | TDP1 (0.57) | TSHRMAPTHSD17B10SMN1; SMN2GAA | |
| SCHEMBL15023787 | 0.84 | ALDH1A1 (0.53) | TSHRMAPTHSD17B10SMN1; SMN2GAA | |
| SCHEMBL28472385 | 0.82 | TLR9 (0.58) | TSHRHSD17B10SMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL26098617 | 0.79 | BCHE (0.61) | TSHRMAPTHSD17B10SMN1; SMN2GAA | |
| SCHEMBL17172445 | 0.78 | MYC (0.71) | TSHRMAPTHSD17B10SMN1; SMN2GAA | |
| SCHEMBL2209512 | 0.78 | TSHR (0.65) | TSHRMAPTHSD17B10SMN1; SMN2GAA | |
| Diethyl Phthalate SCHEMBL29404255 | 0.77 | TSHR (1.00) | TSHRMAPTHSD17B10MAPK1ALDH1A1 | |
| Diethyl Phthalate SCHEMBL5306972 | 0.77 | TSHR (1.00) | TSHRMAPTHSD17B10MAPK1ALDH1A1 | |
| Diethyl Phthalate SCHEMBL22296 | 0.77 | TSHR (1.00) | TSHRMAPTHSD17B10MAPK1ALDH1A1 | |
| SCHEMBL11234450 | 0.77 | ALDH1A1 (0.47) | TSHRMAPTHSD17B10SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130156795-A1 | METHODS FOR INHIBITION OF CELL PROLIFERATION, SYNERGISTIC TRANSCRIPTION MODULES AND USES THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2013-06-20 | — | — | US | disclosed |
| US-20130156795-A1 | METHODS FOR INHIBITION OF CELL PROLIFERATION, SYNERGISTIC TRANSCRIPTION MODULES AND USES THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2013-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130156795-A1 | METHODS FOR INHIBITION OF CELL PROLIFERATION, SYNERGISTIC TRANSCRIPTION MODULES AND USES THEREOF | MKI67, DCX, CTCF | TSHR 2606/4885MAPT 4158/4885HSD17B10 3597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.