SCHEMBL15033665

SCHEMBL15033665

CCOC(=O)C(CO)CCCBr

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CPB2 Q96IY4 2/20 0.45
ALDH1A1 P00352 3/20 0.39
TRPA1 O75762 1/20 0.39
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
KMT2A Q03164 4/20 0.35
MEN1 O00255 2/20 0.35
NPC1 O15118 1/20 0.35
CYP1A2 P05177 1/20 0.34
CYP4F2 P78329 1/20 0.33
CYP4A11 Q02928 1/20 0.33
LMNA P02545 1/20 0.33
HSD17B10 Q99714 1/20 0.33
POLB P06746 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
ALOX15 P16050 1/20 0.32
MGAM O43451 1/20 0.32
GAA P10253 1/20 0.32
SI P14410 1/20 0.32
MGAM2 Q2M2H8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10507615 0.88 ALDH1A1 (0.41) CPB2ALDH1A1TRPA1KMT2AMEN1
SCHEMBL9305715 0.86 CPB2 (0.46) CPB2ALDH1A1TRPA1CA1CA2
SCHEMBL11276526 0.85 CA2 (0.48) CPB2ALDH1A1TRPA1CA1CA2
SCHEMBL11276531 0.85 CA2 (0.48) CPB2ALDH1A1TRPA1CA1CA2
SCHEMBL3176263 0.84 CA2 (0.52) CPB2ALDH1A1CA1CA2KMT2A
SCHEMBL5000143 0.84 CPB2 (0.47) CPB2ALDH1A1CA1CA2KMT2A
SCHEMBL3845206 0.82 CPB2 (0.50) CPB2CA1CA2KMT2AMEN1
SCHEMBL15899433 0.81 ALDH1A1 (0.45) CPB2ALDH1A1TRPA1CA1CA2
SCHEMBL29171186 0.81 CPB2 (0.49) CPB2ALDH1A1TRPA1CA1CA2
SCHEMBL1147236 0.81 CPB2 (0.49) CPB2ALDH1A1TRPA1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013083058-A1 PLATINUM TYPE COMPOUND WITH LEAVING GROUP BEING HYDROXY ACID DERIVATIVE CONTAINING AMINO GROUP OR ALKYL AMINO, AND PREPARATION METHOD AND USE THEREOF 北京市丰硕维康技术开发有限责任公司 (CN) 2013-06-13 WO disclosed