Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.34 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.34 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.34 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9899616 | 0.91 | OPRK1 (0.39) | OPRK1NPY5RPOLBNR1I2SMARCA2 | |
| SCHEMBL15033783 | 0.84 | SOS1 (0.40) | POLBNR1I2SMARCA2SMARCA4PBRM1 | |
| SCHEMBL9940010 | 0.83 | MAPT (0.41) | OPRK1NPY5RPOLBNR1I2SMARCA2 | |
| SCHEMBL9900059 | 0.81 | MAPT (0.54) | OPRK1SIGMAR1ALDH1A1 | |
| SCHEMBL15033831 | 0.75 | PIK3C3 (0.38) | POLBSIGMAR1HSD17B10ALDH1A1HTT | |
| SCHEMBL15033806 | 0.74 | ALDH1A1 (0.36) | SLC6A2SLC6A4SLC6A3ALDH1A1HTT | |
| SCHEMBL9899367 | 0.72 | NR1I2 (0.38) | POLBNR1I2SMARCA2SMARCA4PBRM1 | |
| SCHEMBL9899369 | 0.72 | NR1I2 (0.38) | POLBNR1I2SMARCA2SMARCA4PBRM1 | |
| SCHEMBL16181889 | 0.70 | TYMP (0.36) | NR1I2SMARCA2SMARCA4PBRM1NR1H2 | |
| SCHEMBL3575092 | 0.70 | ALDH1A1 (0.39) | OPRK1NPY5RNR1I2SMARCA2SMARCA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8466186-B2 | Compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-06-18 | — | — | US | disclosed |