SCHEMBL1503449

SCHEMBL1503449

Nc1ccc2sc3ccccc3c2c1N

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.50
MAPT P10636 7/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
TDP1 Q9NUW8 2/20 0.46
BLM P54132 2/20 0.46
POLB P06746 1/20 0.46
DUSP3 P51452 1/20 0.46
PTPN5 P54829 1/20 0.46
PTPN11 Q06124 1/20 0.46
MCL1 Q07820 1/20 0.46
CTDSP1 Q9GZU7 1/20 0.46
ALDH1A1 P00352 4/20 0.46
HPGD P15428 3/20 0.46
RAB9A P51151 3/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
LIMK1 P53667 2/20 0.42
IKBKB O14920 1/20 0.42
NPC1 O15118 2/20 0.38
CYP1A2 P05177 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6303553 0.85 MAOA (0.51) GPR3MAPTMEN1KMT2ATDP1
SCHEMBL3885467 0.81 GPR3 (0.46) GPR3MAPTMEN1KMT2ATDP1
SCHEMBL25008304 0.81 GPR3 (0.46) GPR3MAPTMEN1KMT2ATDP1
SCHEMBL25007980 0.81 GPR3 (0.46) GPR3MAPTMEN1KMT2ATDP1
SCHEMBL5120258 0.81 GPR3 (0.46) GPR3MAPTMEN1KMT2ATDP1
SCHEMBL3872864 0.81 GPR3 (0.46) GPR3MAPTMEN1KMT2ATDP1
SCHEMBL3874450 0.80
SCHEMBL1636538 0.80 GPR3 (0.68) GPR3MAPTMEN1KMT2ATDP1
SCHEMBL3292566 0.79 GPR3 (0.54) GPR3MAPTMEN1KMT2ATDP1
SCHEMBL29671007 0.79 GPR3 (0.54) GPR3MAPTMEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7331997-B2 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof THE PROCTER & GAMBLE COMPANY (US) 2008-02-19 US claimed
US-20050217038-A1 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof PROCTER & GAMBLE COMPANY, THE 2005-10-06 US claimed
EP-0361377-B1 Pervaporation method of separating liquid organic compound mixture through aromatic imide polymer asymmetric membrane UBE INDUSTRIES (JP) 1995-06-28 EP claimed
US-5292963-A Continuous, polyimide separating membrane UBE INDUSTRIES, LTD. (JP) 1994-03-08 US claimed
US-4997462-A Pervaporation method of selectively separating water from an organic material aqueous solution through aromatic imide polymer asymmetric membrane UBE INDUSTRIES, LTD. (JP) 1991-03-05 US claimed
EP-0391699-A1 Pervaporation method of selectively separating water from an organic material aqueous solution through aromatic imide polymer asymmetric membrane UBE INDUSTRIES, LTD. (JP) 1990-10-10 EP claimed
US-4959151-A Pervaporation method of separating liquid organic compound mixture through aromatic imide polymer asymmetric membrane UBE INDUSTRIES (JP) 1990-09-25 US claimed
EP-0361377-A2 Pervaporation method of separating liquid organic compound mixture through aromatic imide polymer asymmetric membrane UBE INDUSTRIES, LTD. (JP) 1990-04-04 EP claimed
CN-113913952-B Polyimide-based electromagnetic shielding film with sandwich structure and preparation method thereof 北京航空航天大学 2023-04-14 CN disclosed
CN-115295879-A Dibenzothiophene electrolyte additive, electrolyte and lithium battery 陕西奥林波斯电力能源有限责任公司 2022-11-04 CN disclosed
US-20210309520-A1 NITROUS OXIDE PURIFICATION METHOD SHOWA DENKO K.K. (JP) 2021-10-07 US disclosed
EP-3858786-A1 NITROUS OXIDE PURIFICATION METHOD Showa Denko K.K. (JP) 2021-08-04 EP disclosed
CN-112533866-A Method for purifying nitrous oxide 昭和电工株式会社 2021-03-19 CN disclosed
US-10765992-B2 Gas separation membrane module and method for gas separation UBE INDUSTRIES, LTD. (JP) 2020-09-08 US disclosed
US-4959151-A Pervaporation method of separating liquid organic compound mixture through aromatic imide polymer asymmetric membrane UBE INDUSTRIES (JP) 1990-09-25 US disclosed
EP-0361377-A2 Pervaporation method of separating liquid organic compound mixture through aromatic imide polymer asymmetric membrane UBE INDUSTRIES, LTD. (JP) 1990-04-04 EP disclosed
EP-0342433-A2 Substituted dibenzothiaphenes AMERICAN CYANAMID COMPANY (US) 1989-11-23 EP disclosed
EP-0263212-A1 Method for removing water vapor from water vapor-containing gas UBE INDUSTRIES, LTD. (JP) 1988-04-13 EP disclosed
US-4718921-A Method for removing water vapor from water vapor-containing gas UBE INDUSTRIES, LTD. (JP) 1988-01-12 US disclosed
US-4690873-A POLYIMIDE FROM DIAMINODIPHENYLENE SULFIDE, SULFOXIDE OR SULFONE UBE INDUSTRIES, LTD. (JP) 1987-09-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050217038-A1 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof KRT18, CKMT1A; CKMT1B, TUBB6 GPR3 4420/4885MAPT 420/4885MEN1 4857/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.