Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 17/20 | 0.75 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.73 |
| ▸ | HTR1A | P08908 | 1/20 | 0.73 |
| ▸ | PKM | P14618 | 1/20 | 0.73 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.73 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.73 |
| ▸ | CNR2 | P34972 | 1/20 | 0.68 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.68 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6754016 | 0.92 | PTGS2 (0.88) | PTGS2PTGS1HTR1APKMGLO1 | |
| SCHEMBL15035977 | 0.89 | PTGS2 (0.71) | PTGS2PTGS1HTR1APKMGLO1 | |
| SCHEMBL16204760 | 0.89 | PTGS2 (0.73) | PTGS2PTGS1GLO1HIF1ACNR2 | |
| SCHEMBL11174704 | 0.89 | PTGS2 (0.85) | PTGS2PTGS1HTR1APKMGLO1 | |
| SCHEMBL11251708 | 0.85 | PTGS2 (0.85) | PTGS2PTGS1HTR1APKMGLO1 | |
| SCHEMBL13813542 | 0.85 | PTGS2 (1.00) | PTGS2PTGS1HTR1APKMGLO1 | |
| SCHEMBL12609003 | 0.85 | PTGS2 (0.85) | PTGS2PTGS1HTR1APKMGLO1 | |
| SCHEMBL12742120 | 0.85 | PTGS2 (0.91) | PTGS2PTGS1HTR1APKMGLO1 | |
| SCHEMBL30077218 | 0.85 | PTGS2 (0.91) | PTGS2PTGS1HTR1APKMGLO1 | |
| Acemetacin SCHEMBL23843 | 0.85 | PTGS2 (1.00) | PTGS2PTGS1HTR1APKMGLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9353214-B2 | Substituted phenacyl molecules and photoresponsive polymers | THE UNIVERSITY OF AKRON (US) | 2016-05-31 | — | — | US | disclosed |
| US-9353214-B2 | Substituted phenacyl molecules and photoresponsive polymers | THE UNIVERSITY OF AKRON (US) | 2016-05-31 | — | — | US | disclosed |
| US-20140323664-A1 | SUBSTITUTED PHENACYL MOLECULES AND PHOTORESPONSIVE POLYMERS | THE UNIVERSITY OF AKRON | 2014-10-30 | — | — | US | disclosed |
| US-20140323664-A1 | SUBSTITUTED PHENACYL MOLECULES AND PHOTORESPONSIVE POLYMERS | THE UNIVERSITY OF AKRON | 2014-10-30 | — | — | US | disclosed |
| WO-2013090892-A1 | SUBSTITUTED PHENACYL MOLECULES AND PHOTORESPONSIVE POLYMERS | THE UNIVERSITY OF AKRON (US) | 2013-06-20 | — | — | WO | disclosed |