Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 16/20 | 0.73 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.72 |
| ▸ | CNR2 | P34972 | 1/20 | 0.72 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.68 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | PTGES | O14684 | 1/20 | 0.67 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.67 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.67 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.67 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | ALB | P02768 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.67 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.67 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.67 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.67 |
| ▸ | AR | P10275 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6754016 | 0.91 | PTGS2 (0.88) | PTGS2AKR1C3CNR2PTGS1HRH4 | |
| SCHEMBL15036529 | 0.89 | PTGS2 (0.75) | PTGS2AKR1C3CNR2PTGS1HRH4 | |
| SCHEMBL11092811 | 0.88 | PTGS2 (0.88) | PTGS2AKR1C3CNR2PTGS1KDM4E | |
| SCHEMBL16204759 | 0.88 | PTGS2 (0.71) | PTGS2AKR1C3CNR2PTGS1KDM4E | |
| SCHEMBL11174704 | 0.87 | PTGS2 (0.85) | PTGS2AKR1C3CNR2PTGS1KDM4E | |
| SCHEMBL10788764 | 0.85 | PTGS2 (0.83) | PTGS2AKR1C3CNR2PTGS1KDM4E | |
| SCHEMBL30426824 | 0.84 | PTGS2 (1.00) | PTGS2AKR1C3CNR2PTGS1KDM4E | |
| SCHEMBL14086813 | 0.84 | PTGS2 (1.00) | PTGS2AKR1C3CNR2PTGS1KDM4E | |
| SCHEMBL11251708 | 0.84 | PTGS2 (0.85) | PTGS2AKR1C3CNR2PTGS1KDM4E | |
| SCHEMBL13813542 | 0.83 | PTGS2 (1.00) | PTGS2AKR1C3CNR2PTGS1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9353214-B2 | Substituted phenacyl molecules and photoresponsive polymers | THE UNIVERSITY OF AKRON (US) | 2016-05-31 | — | — | US | disclosed |
| US-20140323664-A1 | SUBSTITUTED PHENACYL MOLECULES AND PHOTORESPONSIVE POLYMERS | THE UNIVERSITY OF AKRON | 2014-10-30 | — | — | US | disclosed |