SCHEMBL15037258

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15037252	0.93	S1PR4 (0.52)	TPH1PPARDPPARAPPARGS1PR4
	SCHEMBL22449247	0.92	S1PR4 (0.54)	TPH1PPARDPPARAPPARGS1PR4
	SCHEMBL15037155	0.92	S1PR4 (0.54)	TPH1PPARDPPARAPPARGS1PR4
	SCHEMBL15037260	0.91	GPR132 (0.55)	PPARDPPARAPPARGSMPD1PTPN1
	SCHEMBL15037262	0.90	TPH1 (0.61)	TPH1PPARDPPARAPPARGS1PR4
	SCHEMBL15037113	0.90	TPH1 (0.51)	MCHR1TPH1PPARDPPARAPPARG
	SCHEMBL15037264	0.89	PPARG (0.53)	TPH1PPARDPPARAPPARGS1PR4
	SCHEMBL15037115	0.88	KDM4E (0.51)	TPH1S1PR4S1PR1S1PR5S1PR3
	SCHEMBL22448929	0.88	S1PR4 (0.51)	TPH1PPARDPPARAPPARGS1PR4
	SCHEMBL22449192	0.88	MAPT (0.55)	TPH1PPARDPPARAPPARGS1PR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.