Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15037435 | 0.82 | HSD11B1 (0.42) | ALDH1A1SRD5A1MEN1KMT2AHSD11B1 | |
| SCHEMBL22814589 | 0.79 | SMN1; SMN2 (0.44) | ALDH1A1MEN1CYP2C9KMT2AAKR1C3 | |
| SCHEMBL22814449 | 0.79 | ALDH1A1 (0.44) | ALDH1A1OPRM1MEN1CYP2C9KMT2A | |
| SCHEMBL3030218 | 0.78 | ALDH1A1 (0.49) | ALDH1A1DRD4OPRM1SRD5A1MEN1 | |
| SCHEMBL16475260 | 0.76 | ALDH1A1 (0.46) | ALDH1A1DRD4OPRM1SRD5A1MEN1 | |
| SCHEMBL7810392 | 0.74 | MEN1 (0.63) | ALDH1A1OPRM1MEN1CYP2C9KMT2A | |
| SCHEMBL3017592 | 0.73 | ALDH1A1 (0.44) | ALDH1A1DRD4OPRM1SRD5A1MEN1 | |
| SCHEMBL15037487 | 0.72 | GRIN1 (0.39) | ALDH1A1DRD4OPRM1GRIN1GRIN2A | |
| SCHEMBL15037440 | 0.72 | ALDH1A1 (0.40) | ALDH1A1KMT2ABACE1SLC18A3GRM5 | |
| SCHEMBL3023193 | 0.72 | ALDH1A1 (0.47) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3753938-A1 | SUBSTITUTED IMIDAZO-QUINOLINES AS NLRP3 MODULATORS | Innate Tumor Immunity, Inc. (US) | 2020-12-23 | — | — | EP | disclosed |
| US-20130158050-A1 | PIPERIDINE DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 2013-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130158050-A1 | PIPERIDINE DERIVATIVES | GRIN1, GRIN2A, GRIN2C | ALDH1A1 55/4885DRD4 40/4885OPRM1 67/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.