Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15038402 | 0.96 | HPRT1 (0.41) | CYP2C19LMNACA12CA2CA9 | |
| SCHEMBL7757061 | 0.96 | CYP2C19 (0.40) | CYP2C19LMNACA12CA2CA9 | |
| SCHEMBL7906917 | 0.94 | CYP2C19 (0.39) | CYP2C19LMNACA12CA2CA9 | |
| SCHEMBL18594095 | 0.93 | HPRT1 (0.41) | CYP2C19LMNACA12CA2CA9 | |
| SCHEMBL16343993 | 0.93 | HPRT1 (0.41) | CYP2C19LMNACA12CA2CA9 | |
| SCHEMBL21508946 | 0.93 | HPRT1 (0.41) | CYP2C19LMNACA12CA2CA9 | |
| SCHEMBL17995968 | 0.91 | HPRT1 (0.41) | CYP2C19LMNACA12CA2CA9 | |
| SCHEMBL18801433 | 0.91 | HPRT1 (0.41) | CYP2C19LMNACA12CA2CA9 | |
| SCHEMBL19595962 | 0.91 | HPRT1 (0.41) | CYP2C19LMNACA12CA2CA9 | |
| SCHEMBL31191915 | 0.90 | RAB9A (0.39) | CYP2C19LMNACA12CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10665787-B2 | Compounds for electronic devices | MERCK PATENT GMBH (DE) | 2020-05-26 | — | — | US | disclosed |
| US-10424739-B2 | Compounds for electronic devices | MERCK PATENT GMBH (DE) | 2019-09-24 | — | — | US | disclosed |
| US-10008672-B2 | Compounds for electronic devices | MERCK PATENT GMBH (DE) | 2018-06-26 | — | — | US | disclosed |
| US-10008672-B2 | Compounds for electronic devices | MERCK PATENT GMBH (DE) | 2018-06-26 | — | — | US | disclosed |
| EP-3321246-A2 | DOUBLE SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME | LG Chem, Ltd. (KR) | 2018-05-16 | — | — | EP | disclosed |
| US-20180111887-A1 | DOUBLE SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME | LG CHEM, LTD. (KR) | 2018-04-26 | — | — | US | disclosed |
| US-9293712-B2 | Disubstituted pyrene compounds with amino group containing ortho aryl group and devices containing the same | UNIVERSAL DISPLAY CORPORATION (US) | 2016-03-22 | — | — | US | disclosed |
| US-20150102321-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION | 2015-04-16 | — | — | US | disclosed |
| US-20140312287-A1 | Compounds for Electronic Devices | MERCK PATENT GMBH (DE) | 2014-10-23 | — | — | US | disclosed |
| US-20140312287-A1 | Compounds for Electronic Devices | MERCK PATENT GMBH (DE) | 2014-10-23 | — | — | US | disclosed |
| WO-2013087142-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2013-06-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10008672-B2 | Compounds for electronic devices | KCNQ2, DDT, KCNQ1 | CYP2C19 114/4885LMNA 2275/4885CA12 4670/4885 |
| US-10424739-B2 | Compounds for electronic devices | KCNQ2, DDT, KCNQ1 | CYP2C19 114/4885LMNA 2275/4885CA12 4670/4885 |
| US-10665787-B2 | Compounds for electronic devices | KCNQ2, DDT, KCNQ1 | CYP2C19 114/4885LMNA 2275/4885CA12 4670/4885 |
| US-20180111887-A1 | DOUBLE SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME | NR2E3, CRY1, CRY2 | CYP2C19 800/4885LMNA 2928/4885CA12 1653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.