Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TYMS | P04818 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15039711 | 0.86 | TSHR (0.57) | KMT2AP2RX3TSHRALDH1A1MAPT | |
| SCHEMBL10055104 | 0.81 | P2RX3 (0.57) | P2RX3 | |
| SCHEMBL9987765 | 0.76 | P2RX3 (0.54) | P2RX3 | |
| SCHEMBL10254173 | 0.75 | MAPT (0.50) | ATMAPOBEC3GKMT2AP2RX3TSHR | |
| SCHEMBL9983147 | 0.73 | ATM (0.60) | ATMAPOBEC3GKMT2AP2RX3TSHR | |
| SCHEMBL12047012 | 0.73 | P2RX3 (0.63) | P2RX3 | |
| SCHEMBL10254261 | 0.72 | PROKR1 (0.53) | P2RX3ALDH1A1MAPTKDM4E | |
| SCHEMBL15039615 | 0.71 | TSHR (0.58) | P2RX3TSHR | |
| SCHEMBL8280009 | 0.70 | RGS4 (0.50) | KMT2AP2RX3MAPTKDM4EMEN1 | |
| SCHEMBL15462257 | 0.70 | RGS4 (0.51) | P2RX3ALDH1A1MAPTNPSR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2604595-A1 | TRIAZINE DERIVATIVE AND PHARMACEUTICAL COMPOUND THAT CONTAINS SAME AND EXHIBITS ANALGESIC ACTIVITY | Shionogi&Co., Ltd. (JP) | 2013-06-19 | — | — | EP | disclosed |