SCHEMBL15040914

SCHEMBL15040914

Cc1ccc2c3ccccc3n(-c3ccc(-c4ccccc4)cc3)c2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
ATM Q13315 1/20 0.53
AKR1C4 P17516 1/20 0.43
AKR1C3 P42330 1/20 0.43
AKR1C2 P52895 1/20 0.43
AKR1C1 Q04828 1/20 0.43
HDAC4 P56524 1/20 0.43
HTT P42858 3/20 0.39
CYP2C9 P11712 1/20 0.39
AVPR1A P37288 1/20 0.39
ALDH1A1 P00352 6/20 0.39
NR1I2 O75469 1/20 0.39
EGFR P00533 1/20 0.39
ADRA2A P08913 1/20 0.39
ADORA3 P0DMS8 1/20 0.39
TBXA2R P21731 1/20 0.39
PTGS2 P35354 1/20 0.39
OPRD1 P41143 1/20 0.39
PDE4D Q08499 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13957177 0.97 KDM4E (0.52) KDM4EL3MBTL1ATMAKR1C4AKR1C3
SCHEMBL4406988 0.97 KDM4E (0.52) KDM4EL3MBTL1ATMAKR1C4AKR1C3
SCHEMBL17178964 0.94 KDM4E (0.47) KDM4EL3MBTL1ATMAKR1C4AKR1C3
SCHEMBL26226221 0.93 L3MBTL1 (0.50) KDM4EL3MBTL1ATMAKR1C4AKR1C3
SCHEMBL26226199 0.93 L3MBTL1 (0.50) KDM4EL3MBTL1ATMAKR1C4AKR1C3
SCHEMBL13957098 0.92 KDM4E (0.57) KDM4EL3MBTL1ATMAKR1C4AKR1C3
SCHEMBL4401736 0.92 KDM4E (0.57) KDM4EL3MBTL1ATMAKR1C4AKR1C3
SCHEMBL17032735 0.92 KDM4E (0.49) KDM4EL3MBTL1ATMAKR1C4AKR1C3
SCHEMBL17178972 0.91 KDM4E (0.42) KDM4EL3MBTL1ATMAKR1C4AKR1C3
SCHEMBL23679400 0.90 KDM4E (0.53) KDM4EL3MBTL1ATMAKR1C4AKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230354625-A1 PHOTOELECTRIC CONVERSION DEVICE AND LIGHT-EMITTING AND LIGHT-RECEIVING APPARATUS SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2023-11-02 US disclosed
US-20230354625-A1 PHOTOELECTRIC CONVERSION DEVICE AND LIGHT-EMITTING AND LIGHT-RECEIVING APPARATUS SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2023-11-02 US disclosed
US-11706983-B2 Organic light-emitting device SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-07-18 US disclosed
US-20230132153-A1 Organic Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2023-04-27 US disclosed
US-20230132153-A1 Organic Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2023-04-27 US disclosed
EP-3369727-B1 AMINE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LG CHEMICAL LTD (KR) 2021-12-22 EP disclosed
US-20210159422-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2021-05-27 US disclosed
US-10403833-B2 Organic metal complexes MERCK PATENT GMBH (DE) 2019-09-03 US disclosed
EP-2856528-B1 METAL COMPLEXES COMPRISING CONDENSED HETEROAROMATIC RINGS MERCK PATENT GMBH (DE) 2019-07-03 EP disclosed
EP-3147286-B1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME LG CHEMICAL LTD (KR) 2019-04-03 EP disclosed
US-20140371825-A1 ORGANIC METAL COMPLEXES UDC IRELAND LIMITED (IE) 2014-12-18 US disclosed
US-20140371825-A1 ORGANIC METAL COMPLEXES UDC IRELAND LIMITED (IE) 2014-12-18 US disclosed
US-20140358198-A1 ORGANIC SENSITIZERS FOR UP-CONVERSION MERCK PATENT GMBH (DE) 2014-12-04 US disclosed
US-20140358198-A1 ORGANIC SENSITIZERS FOR UP-CONVERSION MERCK PATENT GMBH (DE) 2014-12-04 US disclosed
US-20140350642-A1 Metal Complexes Comprising 1,2,3-Triazoles MERCK PATENT GMBH (DE) 2014-11-27 US disclosed
US-20140350642-A1 Metal Complexes Comprising 1,2,3-Triazoles MERCK PATENT GMBH (DE) 2014-11-27 US disclosed
WO-2013174471-A1 METAL COMPLEXES COMPRISING CONDENSED HETEROAROMATIC RINGS MERCK PATENT GMBH (DE) 2013-11-28 WO disclosed
WO-2013107487-A1 ORGANIC METAL COMPLEXES MERCK PATENT GMBH (DE) 2013-07-25 WO disclosed
WO-2013097920-A1 METAL COMPLEXES COMPRISING 1,2,3-TRIAZOLES MERCK PATENT GMBH (DE) 2013-07-04 WO disclosed
WO-2013087162-A1 ORGANIC SENSITIZERS FOR UP-CONVERSION MERCK PATENT GMBH (DE) 2013-06-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10403833-B2 Organic metal complexes SOD1, ORC3, PPIA KDM4E 3392/4885L3MBTL1 1113/4885ATM 3876/4885
US-20210159422-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device ARNT, SUN2, AHR KDM4E 3263/4885L3MBTL1 337/4885ATM 3759/4885
US-20230132153-A1 Organic Compound CCNA1, DRD1, CYP1A1 KDM4E 2541/4885L3MBTL1 1845/4885ATM 3151/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.