Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15041011 | 0.88 | CES2 (0.48) | TDP1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL19421027 | 0.85 | ATM (0.52) | ATMTDP1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL19421030 | 0.85 | ATM (0.52) | ATMTDP1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL19421029 | 0.85 | ATM (0.52) | ATMTDP1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL19421028 | 0.85 | ATM (0.52) | ATMTDP1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL16271510 | 0.80 | CES2 (0.39) | TDP1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL978869 | 0.80 | KDM4E (0.59) | KDM4EALDH1A1HPGDSMN1; SMN2SRD5A2 | |
| SCHEMBL975343 | 0.80 | ALDH1A1 (0.59) | KDM4EALDH1A1HPGDMAPTLMNA | |
| SCHEMBL29780395 | 0.80 | ALDH1A1 (0.59) | KDM4EALDH1A1HPGDMAPTLMNA | |
| SCHEMBL30776759 | 0.79 | ATM (0.64) | ATMTDP1L3MBTL1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2791275-B1 | ORGANIC SENSITIZERS FOR UP-CONVERSION | MERCK PATENT GMBH (DE) | 2017-05-31 | — | — | EP | disclosed |
| US-20140358198-A1 | ORGANIC SENSITIZERS FOR UP-CONVERSION | MERCK PATENT GMBH (DE) | 2014-12-04 | — | — | US | disclosed |
| US-20140358198-A1 | ORGANIC SENSITIZERS FOR UP-CONVERSION | MERCK PATENT GMBH (DE) | 2014-12-04 | — | — | US | disclosed |
| WO-2013087162-A1 | ORGANIC SENSITIZERS FOR UP-CONVERSION | MERCK PATENT GMBH (DE) | 2013-06-20 | — | — | WO | disclosed |