SCHEMBL978869

SCHEMBL978869

Cc1c2ccccc2c(C)c2cc(C(=O)O)ccc12

nearest known ligand 0.59

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.59
ALDH1A1 P00352 3/20 0.51
HPGD P15428 2/20 0.51
THRB P10828 1/20 0.51
GRIN2D O15399 1/20 0.50
GRIN2A Q12879 1/20 0.50
GRIN2C Q14957 1/20 0.50
TTR P02766 3/20 0.49
PARP1 P09874 1/20 0.49
PTPN1 P18031 1/20 0.46
ACE2 Q9BYF1 3/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
DAO P14920 1/20 0.44
TSHR P16473 1/20 0.44
NAPRT Q6XQN6 1/20 0.44
CES2 O00748 1/20 0.43
CES1 P23141 1/20 0.43
SRD5A2 P31213 1/20 0.43
GRM1 Q13255 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31588057 0.90 KDM4E (0.56) KDM4EALDH1A1HPGDTHRBPTPN1
SCHEMBL975343 0.84 ALDH1A1 (0.59) KDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL2343264 0.83 GRIN2D (0.61) KDM4EALDH1A1HPGDGRIN2DGRIN2A
SCHEMBL19177351 0.83 GRIN2D (0.61) KDM4EALDH1A1HPGDGRIN2DGRIN2A
SCHEMBL10012830 0.83 GRIN2D (0.61) KDM4EALDH1A1HPGDGRIN2DGRIN2A
SCHEMBL8755839 0.83 SRD5A2 (0.48) KDM4EALDH1A1HPGDTHRBDAO
SCHEMBL26117173 0.82 PTPN1 (0.57) KDM4EALDH1A1HPGDTHRBGRIN2D
SCHEMBL15041011 0.80 CES2 (0.48) KDM4EALDH1A1HPGDGRIN2DGRIN2A
SCHEMBL15040959 0.80 ATM (0.43) KDM4EALDH1A1HPGDGRIN2DGRIN2A
SCHEMBL976725 0.79 KIF11 (0.59) KDM4EALDH1A1HPGDPARP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260053393-A1 NEAR-IR GLUCOSE SENSORS PROFUSA INC (US) 2026-02-26 US disclosed
US-20250230174-A1 NEAR-IR GLUCOSE SENSORS PROFUSA, INC. (US) 2025-07-17 US disclosed
US-12285250-B2 Near-IR glucose sensors PROFUSA, INC (US) 2025-04-29 US disclosed
US-20210101915-A1 NEAR-IR GLUCOSE SENSORS PROFUSA, INC. (US) 2021-04-08 US disclosed
US-20210101915-A1 NEAR-IR GLUCOSE SENSORS PROFUSA, INC. (US) 2021-04-08 US disclosed
EP-2478981-B1 SILVER-(CONJUGATED COMPOUND) COMPLEX SUMITOMO CHEMICAL CO (JP) 2020-12-23 EP disclosed
US-10717751-B2 Near-IR glucose sensors PROFUSA, INC. (US) 2020-07-21 US disclosed
US-10717751-B2 Near-IR glucose sensors PROFUSA, INC. (US) 2020-07-21 US disclosed
EP-3562952-A1 NEAR-IR GLUCOSE SENSORS Profusa, Inc. (US) 2019-11-06 EP disclosed
US-20190010170-A1 NEAR-IR GLUCOSE SENSORS PROFUSA, INC. (US) 2019-01-10 US disclosed
US-7524985-B2 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor TERUMO KABUSHIKI KAISHA (JP) 2009-04-28 US disclosed
US-20080319288-A1 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor TERUMO KABUSHIKI KAISHA (JP) 2008-12-25 US disclosed
US-7450980-B2 Intracorporeal substance measuring assembly TERUMO KABUSHIKI KAISHA (JP) 2008-11-11 US disclosed
US-7450980-B2 Intracorporeal substance measuring assembly TERUMO KABUSHIKI KAISHA (JP) 2008-11-11 US disclosed
US-7388110-B2 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor TERUMO KABUSHIKI KAISHA (JP) 2008-06-17 US disclosed
US-20080021236-A1 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor TERUMO KABUSHIKI KAISHA (JP) 2008-01-24 US disclosed
EP-1619229-B1 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor TERUMO CORP (JP) 2007-04-11 EP disclosed
CN-1900212-A Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor TERUMO CORP (JP) 2007-01-24 CN disclosed
US-20060020182-A1 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor TERUMO KABUSHIKI KAISHA 2006-01-26 US disclosed
EP-1619229-A1 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor TERUMO KABUSHIKI KAISHA (JP) 2006-01-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250230174-A1 NEAR-IR GLUCOSE SENSORS IRS1, INSR, SLC2A4 KDM4E 3160/4885ALDH1A1 3159/4885HPGD 3387/4885
US-20210101915-A1 NEAR-IR GLUCOSE SENSORS IRS1, INSR, SLC2A4 KDM4E 3160/4885ALDH1A1 3159/4885HPGD 3387/4885
US-20260053393-A1 NEAR-IR GLUCOSE SENSORS INSR, IRS1, SLC2A4 KDM4E 3774/4885ALDH1A1 3198/4885HPGD 4462/4885
US-20190010170-A1 NEAR-IR GLUCOSE SENSORS IRS1, INSR, SLC2A4 KDM4E 3160/4885ALDH1A1 3159/4885HPGD 3387/4885
US-20080319288-A1 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor ACMSD, QPCT, B3GNT2 KDM4E 2271/4885ALDH1A1 167/4885HPGD 442/4885
US-12285250-B2 Near-IR glucose sensors IRS1, SLC2A4, GPR119 KDM4E 1818/4885ALDH1A1 1177/4885HPGD 2318/4885
US-10717751-B2 Near-IR glucose sensors IRS1, G6PD, SLC2A8 KDM4E 1515/4885ALDH1A1 467/4885HPGD 760/4885
US-20060020182-A1 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor ACMSD, QPCT, B3GNT2 KDM4E 1856/4885ALDH1A1 273/4885HPGD 632/4885
US-20080021236-A1 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor ACMSD, QPCT, B3GNT2 KDM4E 1856/4885ALDH1A1 273/4885HPGD 632/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.