Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.44 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL272092 | 0.83 | TTR (0.56) | PLA2G7ALDH1A1POLBCES2CES1 | |
| SCHEMBL2775065 | 0.81 | PLA2G7 (0.46) | PLA2G7AVPR2AVPR1APPARGPPARA | |
| SCHEMBL3898821 | 0.81 | PARP1 (0.48) | PLA2G7POLBAVPR2AVPR1APPARG | |
| SCHEMBL18900574 | 0.81 | PDK2 (0.44) | PLA2G7NPC1MITFLMNAPOLB | |
| SCHEMBL30951307 | 0.79 | TSHR (0.50) | PLA2G7HTTSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL19002947 | 0.79 | TSHR (0.50) | PLA2G7HTTSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL410258 | 0.79 | PDK2 (0.51) | ALDH1A1NPC1PPARATDP1ATM | |
| SCHEMBL18900043 | 0.77 | PDK2 (0.40) | PLA2G7HTTSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL537623 | 0.76 | CNR2 (0.60) | HTTSMN1; SMN2ALDH1A1NPC1MITF | |
| SCHEMBL14950602 | 0.76 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1POLBTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013087162-A1 | ORGANIC SENSITIZERS FOR UP-CONVERSION | MERCK PATENT GMBH (DE) | 2013-06-20 | — | — | WO | disclosed |