Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.52 |
| ▸ | MYC | P01106 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | RARB | P10826 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ADH5 | P11766 | 1/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14950582 | 1.00 | ALDH1A1 (0.54) | ALDH1A1KDM4EGAAL3MBTL1TSHR | |
| SCHEMBL68014 | 0.96 | ALDH1A1 (0.57) | ALDH1A1KDM4EGAAL3MBTL1TSHR | |
| Hydrochloric Acid SCHEMBL4352471 | 0.93 | ALDH1A1 (0.56) | ALDH1A1KDM4EGAAL3MBTL1TSHR | |
| SCHEMBL14947553 | 0.92 | ALDH1A1 (0.49) | ALDH1A1KDM4EGAAL3MBTL1TSHR | |
| SCHEMBL14947557 | 0.92 | ALDH1A1 (0.49) | ALDH1A1KDM4EGAAL3MBTL1TSHR | |
| SCHEMBL14947555 | 0.88 | HSD17B1 (0.51) | ALDH1A1KDM4EGAAL3MBTL1TSHR | |
| SCHEMBL272092 | 0.86 | TTR (0.56) | ALDH1A1KDM4EGAAL3MBTL1TSHR | |
| SCHEMBL6562948 | 0.85 | HSD17B1 (0.50) | ALDH1A1KDM4EGAAL3MBTL1TSHR | |
| SCHEMBL17656286 | 0.84 | ALDH1A1 (0.49) | ALDH1A1KDM4EGAAL3MBTL1TSHR | |
| SCHEMBL11507830 | 0.83 | RARB (0.63) | ALDH1A1KDM4EGAAL3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130122297-A1 | MOLECULAR GAUGE BLOCKS FOR BUILDING ON THE NANOSCALE | NORTHWESTERN UNIVERSITY (US) | 2013-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130122297-A1 | MOLECULAR GAUGE BLOCKS FOR BUILDING ON THE NANOSCALE | POF1B, PCNA, OGG1 | ALDH1A1 3158/4885KDM4E 869/4885GAA 3361/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.