SCHEMBL15042301

SCHEMBL15042301

Fc1ccc(N(c2ccc(F)cc2)c2cc(-c3ccccc3)c3ccc4c(N(c5ccc(F)cc5)c5ccc(F)cc5)cc(-c5ccccc5)c5ccc2c3c54)cc1

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 1/20 0.35
GRM2 Q14416 2/20 0.34
PTGDR2 Q9Y5Y4 4/20 0.33
MAP2K4 P45985 1/20 0.33
MKNK1 Q9BUB5 1/20 0.33
MKNK2 Q9HBH9 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
HPGD P15428 1/20 0.33
CYP2C19 P33261 1/20 0.33
PTK2B Q14289 1/20 0.33
TOP1 P11387 2/20 0.32
GCGR P47871 1/20 0.32
MAPK14 Q16539 1/20 0.32
PTGS1 P23219 2/20 0.32
PTGS2 P35354 2/20 0.32
NR4A2 P43354 1/20 0.32
ADORA2A P29274 1/20 0.31
ADORA1 P30542 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23849282 0.98 PTGDR2 (0.35) METAP2GRM2PTGDR2MAP2K4MKNK1
SCHEMBL15042299 0.89 BACE1 (0.34) CYP1A2CYP2C9HPGDCYP2C19
SCHEMBL12011512 0.89 BACE1 (0.34) CYP1A2CYP2C9HPGDCYP2C19
SCHEMBL17263977 0.86 ALDH1A1 (0.36) CYP1A2CYP2C9HPGDCYP2C19
SCHEMBL15042343 0.85 IMPDH2 (0.33) CYP1A2CYP2C9HPGDCYP2C19
SCHEMBL13321201 0.85 GRM2 (0.39) GRM2HPGDPTK2BGCGRMAPK14
SCHEMBL12576975 0.84 ALDH1A1 (0.35) METAP2HPGDCYP2C19
SCHEMBL15042297 0.84 MAPT (0.33) METAP2PTGDR2MAP2K4HPGDADORA2A
SCHEMBL12700367 0.83 KDM4E (0.33) PTGDR2CYP1A2CYP2C9HPGDCYP2C19
SCHEMBL12576974 0.83 ALDH1A1 (0.35) METAP2HPGDCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9431614-B2 Organic light emitting device LG DISPLAY CO., LTD. (KR) 2016-08-30 US disclosed
US-9431614-B2 Organic light emitting device LG DISPLAY CO., LTD. (KR) 2016-08-30 US disclosed
US-20130153867-A1 ORGANIC LIGHT EMITTING DEVICE LG DISPLAY CO., LTD. (KR) 2013-06-20 US disclosed
US-20130153867-A1 ORGANIC LIGHT EMITTING DEVICE LG DISPLAY CO., LTD. (KR) 2013-06-20 US disclosed