SCHEMBL15042297

SCHEMBL15042297

Fc1ccc(N(c2ccccc2)c2cc(-c3ccccc3)c3ccc4c(N(c5ccccc5)c5ccc(F)cc5F)cc(-c5ccccc5)c5ccc2c3c54)c(F)c1

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.33
MAP2K4 P45985 1/20 0.33
ADORA1 P30542 2/20 0.32
ADORA2A P29274 1/20 0.32
METAP2 P50579 1/20 0.31
PTGDR2 Q9Y5Y4 1/20 0.31
LMNA P02545 1/20 0.31
HPGD P15428 1/20 0.31
MAOB P27338 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23849282 0.86 PTGDR2 (0.35) MAP2K4METAP2PTGDR2HPGD
SCHEMBL15042301 0.84 METAP2 (0.35) MAP2K4ADORA1ADORA2AMETAP2PTGDR2
SCHEMBL12011512 0.82 BACE1 (0.34) MAPTLMNAHPGDMAOB
SCHEMBL15042299 0.82 BACE1 (0.34) MAPTLMNAHPGDMAOB
SCHEMBL12924616 0.80 CYP1A2 (0.35)
SCHEMBL12023296 0.80 PKM (0.36) MAPTPTGDR2LMNAHPGD
SCHEMBL15461338 0.80 HPGD (0.31) MAPTHPGD
SCHEMBL15042343 0.79 IMPDH2 (0.33) MAPTLMNAHPGDMAOB
SCHEMBL12924615 0.78 DHODH (0.33) MAP2K4ADORA1ADORA2APTGDR2LMNA
SCHEMBL12700367 0.78 KDM4E (0.33) MAPTPTGDR2HPGDMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9431614-B2 Organic light emitting device LG DISPLAY CO., LTD. (KR) 2016-08-30 US disclosed
US-9431614-B2 Organic light emitting device LG DISPLAY CO., LTD. (KR) 2016-08-30 US disclosed
US-20130153867-A1 ORGANIC LIGHT EMITTING DEVICE LG DISPLAY CO., LTD. (KR) 2013-06-20 US disclosed
US-20130153867-A1 ORGANIC LIGHT EMITTING DEVICE LG DISPLAY CO., LTD. (KR) 2013-06-20 US disclosed